Description
Premium Industrial Grade Ephedrine Powder for Research & Manufacturing Applications
PRODUCT DETAILS TABLE
| Specification | Details |
|---|---|
| Brand | Biosynlab |
| Product Name | Ephedrine Powder (Ephedrine Hydrochloride/Sulfate) |
| IUPAC Name | (1R,2S)-2-(methylamino)-1-phenylpropan-1-ol |
| CAS Number | 50-98-6 (HCl); 134-72-5 (base) |
| Molecular Formula | C₁₀H₁₅NO · HCl |
| Molecular Weight | 201.69 g/mol (HCl salt) |
| Chemical Class | Substituted amphetamine / Alkaloid |
| Purity | ≥99.5% (HPLC Verified) |
| Appearance | White to off-white crystalline powder |
| Melting Point | 217-220°C (HCl salt) |
| Solubility | Soluble in water, ethanol; sparingly soluble in ether |
| Storage | Room temperature (15-25°C), desiccated, away from light |
| Packaging | Amber glass vial with PTFE seal |
| Quantities | 10g, 25g, 50g, 100g, 250g, 500g, 1kg, bulk |
| Analysis | COA, NMR, MS, FTIR, chiral HPLC included |
| Shipping | Express courier, tracked, discreet |
| Regions | USA (List I chemical), UK, Germany, Netherlands, EU |
Ephedrine Powder (Ephedrine Hydrochloride or Sulfate) represents a naturally occurring alkaloid and critical pharmaceutical compound with established applications in respiratory medicine, cardiovascular research, and as a precursor chemical for various pharmaceutical syntheses. As a sympathomimetic amine with both alpha and beta-adrenergic activity, ephedrine has been utilized clinically for decades as a bronchodilator, decongestant, and pressor agent. Biosynlab delivers pharmaceutical-grade ephedrine with certified ≥99.5% purity and high enantiomeric purity, supporting cutting-edge research across USA (DEA List I chemical licensed institutions), United Kingdom, European Union, and international pharmaceutical and scientific markets.
The stereochemistry of ephedrine is critical for its pharmacological activity, with the (1R,2S)-(-)-ephedrine enantiomer being the naturally occurring and most pharmacologically active form. This structural configuration, featuring a beta-hydroxy group on the phenethylamine backbone, distinguishes ephedrine from other sympathomimetics and contributes to its unique pharmacokinetic profile including oral bioavailability and reduced CNS penetration compared to amphetamines. Pharmaceutical manufacturers and research institutions in London, Berlin, Amsterdam, New York, and Basel rely on Biosynlab ephedrine for formulation development, chiral synthesis research, and as a reference standard in analytical applications.
Chemical Properties & Structural Characterization
Ephedrine Hydrochloride belongs to the substituted phenethylamine chemical class, specifically the beta-hydroxyphenethylamine subclass characterized by a hydroxyl group on the beta-carbon and a methyl group on the alpha-carbon relative to the amine.
Key Structural Features:
- Core Scaffold: Beta-hydroxyphenethylamine backbone
- Substitutions: N-methyl, beta-hydroxy, alpha-methyl
- Stereochemistry: (1R,2S)-configuration (natural ephedrine; pseudoephedrine is diastereomer)
- Salt Forms: Hydrochloride (most common), sulfate, base
- Physical State: Crystalline powder (HCl salt) or prismatic crystals
- Chirality: Two chiral centers (erythro configuration)
Analytical Characteristics:
- UV Absorption: 251 nm, 257 nm, 263 nm (fine structure, phenyl ring)
- Retention Time (HPLC): 5.8-6.5 minutes (C18 column, chiral separation)
- Chiral HPLC: Baseline separation of ephedrine vs. pseudoephedrine, enantiomeric purity
- Mass Spec m/z: 166.1 [M+H]+ (free base), 148.1 [M+H-H₂O]+, 133.1 [M+H-CH₃NH₂]+
- NMR Signatures: N-methyl doublet (2.4-2.6 ppm), methine proton (3.8-4.2 ppm), benzylic proton (4.6-5.0 ppm), phenyl protons (7.2-7.4 ppm), exchangeable OH/NH protons
Research Applications & Scientific Utility
Pharmaceutical Research & Development:
Ephedrine serves as a critical compound for:
- Bronchodilator formulation development (asthma, COPD)
- Nasal decongestant research (sympathomimetic vasoconstriction)
- Pressor agent studies (hypotension treatment)
- Chiral synthesis and resolution methodology
- Prodrug and salt form optimization
- Bioavailability and pharmacokinetic studies
- Drug interaction studies (MAO inhibitors, stimulants)
