Description
Adrafinil Powder | Premium Nootropic Research Compound | Cognitive Enhancement Studies
Welcome to BiosynLab, your trusted source for high-purity nootropic research compounds. Our Adrafinil Powder represents pharmaceutical-grade quality for researchers investigating eugeroic compounds, wakefulness-promoting agents, and cognitive enhancement mechanisms. Synthesized to rigorous analytical standards, this prodrug of modafinil serves laboratories across Europe, the United Kingdom, and the United States conducting legitimate neuropharmacological research.
What Is Adrafinil?
Adrafinil (CRL-40028, Olmifon) is a synthetic nootropic compound belonging to the eugeroic class of wakefulness-promoting agents. Chemically designated as 2-benzhydrylsulfinylethanehydroxamic acid, this compound functions as a prodrug to modafinil, converting in vivo via hepatic metabolism. First synthesized in 1974 by the French pharmaceutical company Laboratoires Lafon, adrafinil has become an essential reference material for research into orexinergic neurotransmission, histamine release, and dopaminergic modulation.
Unlike traditional stimulants, adrafinil exhibits a unique pharmacological profile characterized by enhanced alertness without the hyperactivity, jitteriness, or cardiovascular strain associated with amphetamine-class compounds. This distinctive mechanism makes it invaluable for neuropharmacological research, sleep disorder studies, and investigations into cognitive enhancement pathways.
Origin and Synthesis Excellence
Our adrafinil powder originates from certified European laboratories employing advanced organic synthesis protocols. The manufacturing process involves:
Synthesis Pathway:
- Starting from benzhydryl mercaptan and chloroacetic acid derivatives
- Oxidation to sulfoxide intermediate
- Conversion to hydroxamic acid functionality
- Crystallization and purification to analytical grade
Quality Verification:
- HPLC purity analysis (≥99%)
- NMR spectroscopic confirmation of structure
- Mass spectrometry verification
- Residual solvent screening (GC-MS)
- Heavy metals testing (ICP-MS)
- Melting point determination (148-150°C)
Each batch is accompanied by a comprehensive Certificate of Analysis documenting these parameters, ensuring reproducible results for your research applications.
Chemical Profile and Specifications
Molecular Characteristics:
- IUPAC Name: 2-(Benzhydrylsulfinyl)-N-hydroxyacetamide
- Molecular Formula: C₁₅H₁₅NO₃S
- Molecular Weight: 289.35 g/mol
- CAS Number: 63547-13-7
- Appearance: White to off-white crystalline powder
- Solubility: Soluble in DMSO, ethanol; slightly soluble in water
Available Quantities:
- 1 gram research sample
- 5 gram laboratory pack
- 10 gram institutional quantity
- 25+ gram bulk synthesis (inquire)
Research Applications and Suitability
Neuropharmacology Research: Adrafinil serves as a critical tool for investigating the orexin/hypocretin system, histaminergic pathways, and atypical dopamine reuptake mechanisms. Researchers utilize this compound to study wakefulness promotion distinct from classical psychostimulant action.
Cognitive Enhancement Studies: Academic institutions examine adrafinil’s effects on working memory, executive function, and attentional processes in preclinical models. Its prodrug nature provides insights into hepatic metabolism and bioavailability research.
Sleep Disorder Research: Laboratories studying narcolepsy, shift work sleep disorder, and excessive daytime sleepiness employ adrafinil as a reference compound for comparative pharmacology with modafinil and armodafinil.
Metabolism Investigations: The conversion of adrafinil to modafinil via hepatic enzymes (primarily cytochrome P450) offers research opportunities in pharmacokinetics, first-pass metabolism, and prodrug design optimization.
Suitable For:
- University neuropharmacology departments
- Pharmaceutical research institutions
- Contract research organizations (CROs)
- Independent chemical research laboratories
- Nootropic and cognitive science researchers
Proper Storage and Longevity
Adrafinil powder exhibits excellent stability when stored under appropriate conditions:
Temperature: Room temperature (20-25°C) storage is acceptable; refrigeration (2-8°C) extends shelf life for long-term preservation.
Container: Store in airtight amber glass vials with desiccant to prevent moisture absorption and oxidative degradation.
Light Protection: While less photosensitive than tryptamine compounds, protection from direct sunlight maintains optimal purity.
Shelf Life: 24-36 months when stored properly. Annual purity verification recommended for critical research applications.
Hygroscopicity: Moderate—ensure containers are properly sealed between uses to prevent clumping and degradation.
Premium Packaging and Presentation
All adrafinil orders ship in professional, discreet packaging suitable for laboratory receiving:
- Primary Container: Pharmaceutical-grade amber glass vial with PTFE-lined phenolic cap
- Secondary Protection: Vacuum-sealed Mylar bag with oxygen absorber
- Documentation: Batch-specific Certificate of Analysis, Safety Data Sheet (SDS), and handling guidelines
- Labeling: Chemical name, CAS number, molecular formula, storage conditions, lot number, and expiration date
Regulatory Status and Responsible Research
Legal Classification: Adrafinil occupies a unique regulatory position. In the United States, it is not scheduled under the Controlled Substances Act and is not FDA-approved for human consumption. It is marketed as a research chemical or dietary supplement ingredient. In the United Kingdom, it is not controlled under the Misuse of Drugs Act but may fall under the Psychoactive Substances Act depending on intended use. European regulations vary by member state—researchers should verify local compliance requirements.
Research Use Only: This product is sold explicitly for in vitro research, analytical reference, and laboratory investigation. It is NOT intended for human consumption, veterinary use, or diagnostic applications.
Health Disclaimer: We make no therapeutic, medical, or cognitive enhancement claims. Any reference to pharmacological activity is for research context only. Adrafinil may interact with hepatic enzyme systems and should be handled with appropriate safety protocols.
Compliance: Customers are responsible for understanding and adhering to applicable regulations in their jurisdiction regarding possession, use, and importation of research chemicals.
Why Researchers Choose BiosynLab Adrafinil
Our reputation for analytical excellence extends to our nootropic compound collection. When your research demands consistent, verifiable quality for eugeroic pharmacology studies, BiosynLab delivers the purity, documentation, and reliability that peer-reviewed research requires.
Order your adrafinil powder today and experience the BiosynLab standard of research chemical excellence.
