Description
5-Bromo-DMT (5-Bromo-N,N-dimethyltryptamine)
CAS: 17274-65-6 | C₁₂H₁₅BrN₂ | Molecular Weight: 267.17 g/mol
Catalog Number: BSN-5BRDMT-100
Availability: In Stock
Grade: Research Grade (≥98% purity by HPLC)
Form: Crystalline Powder
Quantity Options: 100mg | 250mg | 500mg | 1g
Product Overview
5-Bromo-DMT is a synthetic tryptamine compound and brominated analog of N,N-dimethyltryptamine (DMT), distinguished by the substitution of a bromine atom at the 5-position of the indole ring. This structural modification alters the compound’s pharmacokinetic profile and receptor binding characteristics, making it a valuable reference standard for serotonin receptor pharmacology and psychedelic research.
At BiosynLab.com, we supply 5-Bromo-DMT exclusively for authorized research institutions, analytical laboratories, and neuropharmacology research programs. Each batch undergoes rigorous analytical verification using HPLC-DAD and LC-MS/MS to confirm structural identity, purity ≥98%, and absence of synthesis byproducts. Our synthesis protocols follow strict quality control standards to ensure batch-to-batch consistency essential for reproducible research outcomes.
Chemical Properties
| Property | Specification |
|---|---|
| CAS Number | 17274-65-6 |
| Chemical Name | 5-Bromo-N,N-dimethyltryptamine |
| Molecular Formula | C₁₂H₁₅BrN₂ |
| Molecular Weight | 267.17 g/mol |
| IUPAC Name | 2-(5-bromo-1H-indol-3-yl)-N,N-dimethylethanamine |
| Appearance | Off-white to light tan crystalline powder |
| Melting Point | 178-182°C |
| Solubility | Soluble in DMSO, methanol, ethanol; insoluble in water |
| Storage Conditions | -20°C, desiccated, protected from light and moisture |
| Stability | Stable for 24 months under recommended storage |
Research Applications
Serotonin Receptor Pharmacology
5-Bromo-DMT serves as a critical tool compound for studying serotonin 5-HT₂A and 5-HT₂C receptor subtypes. Its modified binding affinity compared to parent tryptamines provides researchers with comparative data on structure-activity relationships (SAR) within the indolealkylamine class.
Psychedelic Research Programs
Investigation of mechanistic pathways underlying psychedelic compounds, including receptor binding kinetics, signal transduction cascades, and downstream neuromodulatory effects in appropriate cellular and animal models.
Neurochemical Analysis
Reference standard for HPLC, GC-MS, and LC-MS/MS method development in forensic toxicology, analytical chemistry, and metabolomics research. High purity ensures accurate calibration curves and reliable quantification in complex matrices.
Comparative Pharmacology Studies
Research examining halogen substitution effects on tryptamine pharmacology, including comparisons with 5-MeO-DMT, 5-F-DMT, and unsubstituted DMT regarding receptor affinity, metabolic stability, and behavioral pharmacology.
Marine Natural Product Research
5-Bromo-DMT occurs naturally in certain marine sponges (Smenospongia aurea). Synthetic material supports research into biosynthetic pathways, ecological functions, and marine pharmacology applications.





