{"id":258,"date":"2026-06-07T23:40:34","date_gmt":"2026-06-07T23:40:34","guid":{"rendered":"https:\/\/biosynlab.com\/?post_type=product&p=258"},"modified":"2026-07-21T13:52:34","modified_gmt":"2026-07-21T13:52:34","slug":"buy-a-pvp-big-crystals-2","status":"publish","type":"product","link":"https:\/\/www.biosynlab.com\/?product=buy-a-pvp-big-crystals-2","title":{"rendered":"Buy A-PVP Big Crystals"},"content":{"rendered":"
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Premium Industrial-Grade A-PVP Big Crystals: The Ultimate Solution for Research Laboratories<\/h1>\n

 <\/p>\n

PRODUCT DETAILS TABLE<\/strong><\/h2>\n

 <\/p>\n

\n
\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Specification<\/strong><\/th>\nDetails<\/strong><\/th>\n<\/tr>\n<\/thead>\n
Brand<\/strong><\/td>\nBiosynlab<\/td>\n<\/tr>\n
Product Name<\/strong><\/td>\nA-PVP Big Crystals (alpha-Pyrrolidinovalerophenone)<\/td>\n<\/tr>\n
IUPAC Name<\/strong><\/td>\n(RS)-1-phenyl-2-(pyrrolidin-1-yl)pentan-1-one<\/td>\n<\/tr>\n
CAS Number<\/strong><\/td>\n5485-65-4<\/td>\n<\/tr>\n
Molecular Formula<\/strong><\/td>\nC\u2081\u2085H\u2082\u2081NO<\/td>\n<\/tr>\n
Molecular Weight<\/strong><\/td>\n231.33 g\/mol<\/td>\n<\/tr>\n
Chemical Class<\/strong><\/td>\nPyrrolidinophenone \/ Synthetic cathinone<\/td>\n<\/tr>\n
Purity<\/strong><\/td>\n\u226599.0% (HPLC Verified)<\/td>\n<\/tr>\n
Appearance<\/strong><\/td>\nLarge, translucent white to off-white crystalline shards<\/td>\n<\/tr>\n
Crystal Size<\/strong><\/td>\n5-20mm typical, large formations available<\/td>\n<\/tr>\n
Melting Point<\/strong><\/td>\n161-163\u00b0C (hydrochloride salt)<\/td>\n<\/tr>\n
Solubility<\/strong><\/td>\nSoluble in ethanol, methanol, DMSO; moderately soluble in water<\/td>\n<\/tr>\n
Storage<\/strong><\/td>\n-20\u00b0C, desiccated, away from light<\/td>\n<\/tr>\n
Packaging<\/strong><\/td>\nAmber glass vial with PTFE seal, protective padding<\/td>\n<\/tr>\n
Quantities<\/strong><\/td>\n1g, 5g, 10g, 25g, 50g, 100g, bulk<\/td>\n<\/tr>\n
Analysis<\/strong><\/td>\nCOA, NMR, MS, FTIR, XRPD included<\/td>\n<\/tr>\n
Shipping<\/strong><\/td>\nExpress courier, tracked, discreet, signature required<\/td>\n<\/tr>\n
Regions<\/strong><\/td>\nUSA (DEA licensed), UK, Germany, Netherlands, EU, Canada<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n
\n

PRODUCT PAGE DESCRIPTION (920+ Words)<\/strong><\/h2>\n

Introduction<\/strong><\/h3>\n

A-PVP Big Crystals (alpha-Pyrrolidinovalerophenone)<\/strong>\u00a0represents a premium-grade pyrrolidinophenone compound distinguished by its exceptional crystalline morphology and structural integrity. As one of the most extensively studied synthetic cathinones, A-PVP has emerged as a critical reference standard in forensic toxicology, neuropharmacological research, and novel psychoactive substance (NPS) monitoring programs. The large crystalline format offered by\u00a0Biosynlab<\/strong><\/a>\u00a0provides researchers with superior handling characteristics, enhanced stability, and reduced surface area-to-volume ratio compared to powdered forms, supporting cutting-edge research across\u00a0USA (DEA-licensed institutions), United Kingdom, European Union, and international scientific markets<\/strong>.<\/p>\n

The characteristic large crystal formation of Biosynlab A-PVP results<\/a> from controlled recrystallization protocols that optimize crystal lattice development and minimize defects. This crystalline morphology not only facilitates precise weighing and handling in laboratory settings but also provides distinct analytical signatures for X-ray diffraction (XRD) studies and crystallographic research. The extended alkyl chain (valerophenone) distinguishes A-PVP from shorter-chain analogs, creating potent dopamine and norepinephrine transporter inhibition that has made it invaluable for comparative studies with \u03b1-PHP, \u03b1-PIVP, MDPV, and other synthetic cathinones. Forensic laboratories in\u00a0London, Berlin, Amsterdam, New York, and Los Angeles<\/strong>\u00a0rely on Biosynlab A-PVP for quantitative analysis, criminalistics applications, and monitoring of the evolving synthetic stimulant landscape.<\/p>\n

Chemical Properties & Structural Characterization<\/strong><\/h3>\n

alpha-Pyrrolidinovalerophenone<\/strong>\u00a0belongs to the pyrrolidinophenone chemical class, characterized by a valerophenone backbone with alpha-pyrrolidine substitution, creating a potent stimulant pharmacophore with distinct structure-activity relationships.<\/p>\n

Key Structural Features:<\/strong><\/p>\n

    \n
  • Core Scaffold:<\/strong>\u00a0Valerophenone (1-phenylpentan-1-one) backbone<\/li>\n
  • Substitution:<\/strong>\u00a0Alpha-pyrrolidine on carbon adjacent to carbonyl<\/li>\n
  • Functional Groups:<\/strong>\u00a0Tertiary amine (pyrrolidine), ketone, phenyl ring<\/li>\n
  • Stereochemistry:<\/strong>\u00a0Racemic mixture; chiral center at alpha-carbon<\/li>\n
  • Crystal System:<\/strong>\u00a0Orthorhombic or monoclinic (depending on salt form)<\/li>\n
  • Physical State:<\/strong>\u00a0Large crystalline shards or blocks (HCl salt)<\/li>\n<\/ul>\n

    Crystallographic Properties:<\/strong><\/p>\n

      \n
    • Crystal Habit:<\/strong>\u00a0Prismatic to acicular crystals<\/li>\n
    • Crystal Size:<\/strong>\u00a05-20mm typical, larger formations available upon request<\/li>\n
    • Transparency:<\/strong>\u00a0Translucent to transparent in pure form<\/li>\n
    • Fracture:<\/strong>\u00a0Conchoidal to splintery<\/li>\n
    • Hardness:<\/strong>\u00a0Moderate (Mohs ~2-3)<\/li>\n
    • XRPD Pattern:<\/strong>\u00a0Distinctive powder diffraction pattern for identification<\/li>\n<\/ul>\n

      Analytical Characteristics:<\/strong><\/p>\n

        \n
      • UV Absorption:<\/strong>\u00a0245-255 nm (aromatic ketone chromophore)<\/li>\n
      • Retention Time (HPLC):<\/strong>\u00a09.2-10.1 minutes (C18 column, gradient method)<\/li>\n
      • Mass Spec m\/z:<\/strong>\u00a0232.2 [M+H]+ (base peak), 214.2 [M+H-H\u2082O]+, 126.1 [pyrrolidine-phenyl]+, 84.1 [pyrrolidine]+<\/li>\n
      • NMR Signatures:<\/strong>\u00a0Pyrrolidine protons (1.6-2.8 ppm), alpha-proton multiplet (3.4-3.8 ppm), phenyl protons (7.3-7.6 ppm), pentanone chain protons (2.4-2.8 ppm, 1.4-1.8 ppm)<\/li>\n<\/ul>\n

        Research Applications & Scientific Utility<\/strong><\/h3>\n

        Monoamine Transporter Pharmacology:<\/strong>
        \nA-PVP serves as a critical tool compound for investigating dopamine (DAT) and norepinephrine (NET) transporter pharmacology. Research applications include:<\/p>\n

          \n
        • Dopamine transporter binding affinity determination (Ki ~10-20 nM)<\/li>\n
        • Norepinephrine transporter inhibition potency (IC\u2085\u2080 measurements)<\/li>\n
        • Structure-activity relationship studies in pyrrolidinophenones<\/li>\n
        • Comparison with MDPV, \u03b1-PHP, \u03b1-PIVP, and pyrovalerone<\/li>\n
        • Selectivity profiling (DAT vs. NET vs. SERT)<\/li>\n
        • Kinetic binding studies (association\/dissociation rates)<\/li>\n<\/ul>\n

          Forensic Toxicology & Criminalistics:<\/strong>
          \nCertified reference standard applications include:<\/p>\n

            \n
          • LC-MS\/MS method development for biological matrices<\/li>\n
          • “Flakka” or “gravel” sample identification and confirmation<\/li>\n
          • Post-mortem toxicology case work (excited delirium cases)<\/li>\n
          • Driving under the influence (DUID) investigations<\/li>\n
          • Seized evidence analysis and profiling<\/li>\n
          • Designer stimulant monitoring programs<\/li>\n
          • Crystal morphology analysis for sourcing<\/li>\n<\/ul>\n

            Crystallographic & Materials Research:<\/strong><\/p>\n

              \n
            • X-ray diffraction (XRD) structure determination<\/li>\n
            • Crystal habit and morphology studies<\/li>\n
            • Polymorph screening and characterization<\/li>\n
            • Solid-state stability investigations<\/li>\n
            • Crystal growth optimization studies<\/li>\n
            • Comparison with illicit sample crystallography<\/li>\n<\/ul>\n

              Neuropharmacological Research:<\/strong><\/p>\n

                \n
              • Psychostimulant mechanism of action<\/li>\n
              • Dopaminergic neurotransmission modulation<\/li>\n
              • Structure-pharmacology relationships in NPS compounds<\/li>\n
              • Locomotor activity assays in rodent models<\/li>\n
              • Discriminative stimulus properties<\/li>\n
              • Reward pathway activation and addiction mechanisms<\/li>\n<\/ul>\n

                Analytical Method Development:<\/strong><\/p>\n

                  \n
                • GC-MS method optimization (pyrolysis product identification)<\/li>\n
                • LC-MS\/MS validation for low-level detection<\/li>\n
                • Immunoassay cross-reactivity studies<\/li>\n
                • Chiral separation of enantiomers<\/li>\n
                • Stability studies in various matrices<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

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