{"id":533,"date":"2026-06-07T23:41:36","date_gmt":"2026-06-07T23:41:36","guid":{"rendered":"https:\/\/biosynlab.com\/?post_type=product&p=533"},"modified":"2026-06-23T03:11:09","modified_gmt":"2026-06-23T03:11:09","slug":"lgd-4033-powder-ligandrol","status":"publish","type":"product","link":"https:\/\/www.biosynlab.com\/?product=lgd-4033-powder-ligandrol","title":{"rendered":"LGD-4033 Powder (Ligandrol)"},"content":{"rendered":"

LGD-4033 Powder (Ligandrol) – Industrial Grade Bulk Supply<\/h1>\n

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Product Details Table<\/strong><\/h2>\n

 <\/p>\n

\n
\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Attribute<\/strong><\/th>\nSpecification<\/strong><\/th>\n<\/tr>\n<\/thead>\n
Brand<\/strong><\/td>\nBioSynLab Research Compounds<\/td>\n<\/tr>\n
Product Name<\/strong><\/td>\nLGD-4033 (Ligandrol)<\/td>\n<\/tr>\n
Synonyms<\/strong><\/td>\nLigandrol, VK5211, Anabolicum<\/td>\n<\/tr>\n
CAS Number<\/strong><\/td>\n1165910-22-4<\/td>\n<\/tr>\n
Molecular Formula<\/strong><\/td>\nC\u2081\u2084H\u2081\u2082F\u2086N\u2082O<\/td>\n<\/tr>\n
Molecular Weight<\/strong><\/td>\n338.25 g\/mol<\/td>\n<\/tr>\n
Chemical Class<\/strong><\/td>\nSelective Androgen Receptor Modulator (SARM)<\/td>\n<\/tr>\n
Purity<\/strong><\/td>\n\u226599.0% (HPLC Verified)<\/td>\n<\/tr>\n
Appearance<\/strong><\/td>\nWhite to Off-White Crystalline Powder<\/td>\n<\/tr>\n
Form<\/strong><\/td>\nMicronized Crystalline Powder<\/td>\n<\/tr>\n
Particle Size<\/strong><\/td>\n20-50 microns<\/td>\n<\/tr>\n
Bulk Density<\/strong><\/td>\n0.4-0.6 g\/cm\u00b3<\/td>\n<\/tr>\n
Storage<\/strong><\/td>\n-20\u00b0C, Desiccated, Argon Atmosphere<\/td>\n<\/tr>\n
Packaging<\/strong><\/td>\nAmber Borosilicate Vials with PTFE Seals<\/td>\n<\/tr>\n
Available Quantities<\/strong><\/td>\n1g, 5g, 10g, 25g, 50g, 100g<\/td>\n<\/tr>\n
Documentation<\/strong><\/td>\nCOA, HPLC, NMR, MS, MSDS, Stability Data<\/td>\n<\/tr>\n
Shipping<\/strong><\/td>\nAmbient or Refrigerated, Discrete<\/td>\n<\/tr>\n
Origin<\/strong><\/td>\nEU\/GMP Certified Laboratory<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n
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LGD-4033 (Ligandrol) Powder<\/a> | High-Potency SARM for Androgen Receptor Research | BioSynLab<\/strong><\/h3>\n

BioSynLab<\/strong>\u00a0presents\u00a0pharmaceutical-grade LGD-4033 (Ligandrol)<\/strong>\u00a0in\u00a0micronized powder form<\/strong>\u00a0for\u00a0advanced androgen receptor research<\/strong>,\u00a0formulation development<\/strong>, and\u00a0large-scale analytical studies<\/strong>. As one of the\u00a0most potent non-steroidal SARMs<\/strong>\u00a0documented in\u00a0preclinical literature<\/strong>, Ligandrol powder offers\u00a0maximum flexibility<\/strong>\u00a0for\u00a0custom formulation preparation<\/strong>,\u00a0dose-response studies<\/strong>, and\u00a0institutional-scale research programs<\/strong>.<\/p>\n

Chemical Architecture & Superior Potency<\/strong><\/h3>\n

LGD-4033 (Ligandrol, VK5211)<\/strong>\u00a0maintains the\u00a0same exceptional pharmacological profile<\/strong>\u00a0as our\u00a0capsule formulation<\/strong>, now in\u00a0versatile powder presentation<\/strong>:<\/p>\n

Structural Features:<\/strong><\/p>\n

    \n
  • Quinoline Core:<\/strong>\u00a0Fused bicyclic aromatic system for\u00a0optimal AR binding<\/strong><\/li>\n
  • Dual Trifluoromethyl Groups:<\/strong>\u00a0CF\u2083 substituents<\/strong>\u00a0enhancing\u00a0metabolic stability<\/strong><\/li>\n
  • Pyrrolidine Ring:<\/strong>\u00a0Five-membered nitrogen heterocycle for\u00a0binding specificity<\/strong><\/li>\n
  • Amide Linkage:<\/strong>\u00a0Critical pharmacophore for\u00a0hydrogen bonding<\/strong><\/li>\n<\/ul>\n

    Mechanism of Action:<\/strong><\/p>\n

      \n
    • High-Affinity AR Agonist:<\/strong>\u00a0Ki ~1 nM (highest affinity among commercial SARMs<\/strong>)<\/li>\n
    • Tissue Selectivity:<\/strong>\u00a0Anabolic effects<\/strong>\u00a0in\u00a0muscle\/bone<\/strong>,\u00a0minimal androgenic activity<\/strong><\/li>\n
    • Superior Potency:<\/strong>\u00a0Significantly more potent<\/strong>\u00a0than\u00a0first-generation SARMs<\/strong><\/li>\n
    • Oral Bioavailability:<\/strong>\u00a0Excellent systemic exposure<\/li>\n<\/ul>\n

      Physicochemical Properties:<\/strong><\/p>\n

        \n
      • Molecular weight:<\/strong>\u00a0338.25 g\/mol<\/li>\n
      • Calculated LogP:<\/strong>\u00a03.6 (optimal lipophilicity)<\/li>\n
      • Melting point:<\/strong>\u00a0105-110\u00b0C (crystalline solid)<\/li>\n
      • Chirality:<\/strong>\u00a0Single enantiomer (>99% ee)<\/li>\n<\/ul>\n

        Powder Engineering & Research Advantages<\/strong><\/h3>\n

        Our\u00a0micronized LGD-4033 powder<\/strong>\u00a0(20-50\u03bcm) offers\u00a0distinct advantages<\/strong>\u00a0for\u00a0advanced research<\/strong>:<\/p>\n

        Solubility Profile:<\/strong><\/p>\n

          \n
        • Dimethyl sulfoxide (DMSO):<\/strong>\u00a0\u2265100 mg\/mL (preferred stock solvent)<\/li>\n
        • Ethanol:<\/strong>\u00a0\u226580 mg\/mL (very good)<\/li>\n
        • Methanol:<\/strong>\u00a0\u226590 mg\/mL (excellent)<\/li>\n
        • Acetonitrile:<\/strong>\u00a0\u226570 mg\/mL (good)<\/li>\n
        • Water:<\/strong>\u00a0<1 mg\/mL (requires co-solvent)<\/li>\n
        • PEG-400:<\/strong>\u00a0\u226560 mg\/mL (formulation compatible)<\/li>\n<\/ul>\n

          Stock Solution Preparation:<\/strong><\/p>\n

            \n
          • 10 mM DMSO stock:<\/strong>\u00a0Dissolve 3.38mg in 1mL anhydrous DMSO<\/li>\n
          • Storage:<\/strong>\u00a0-80\u00b0C in\u00a0aliquoted portions<\/strong><\/li>\n
          • Working solutions:<\/strong>\u00a0Prepare fresh daily in\u00a0aqueous buffers<\/strong><\/li>\n<\/ul>\n

            Powder Handling Properties:<\/strong><\/p>\n

              \n
            • Flowability:<\/strong>\u00a0Excellent (Carr index <15)<\/li>\n
            • Compressibility:<\/strong>\u00a0Suitable for\u00a0tablet formulation research<\/strong><\/li>\n
            • Hygroscopicity:<\/strong>\u00a0Low (stable under ambient conditions)<\/li>\n
            • Electrostatic charge:<\/strong>\u00a0Minimal (anti-static processing)<\/li>\n<\/ul>\n

              Formulation Flexibility:<\/strong><\/p>\n

                \n
              • Custom capsule preparation<\/strong>\u00a0(research formulation development)<\/li>\n
              • Suspension formulation<\/strong>\u00a0(aqueous vehicles)<\/li>\n
              • Transdermal delivery<\/strong>\u00a0research (liposomal formulations)<\/li>\n
              • Injectable formulations<\/strong>\u00a0(sterile solution preparation)<\/li>\n<\/ul>\n

                Analytical Characterization & Quality Verification<\/strong><\/h3>\n

                Each\u00a0BioSynLab LGD-4033 powder<\/strong>\u00a0batch undergoes\u00a0comprehensive analytical profiling<\/strong>:<\/p>\n

                Chromatographic Analysis:<\/strong><\/p>\n

                  \n
                • HPLC-UV (220nm):<\/strong>\u00a0\u226599.0% purity<\/li>\n
                • Chiral HPLC:<\/strong>\u00a0Enantiomeric purity >99% ee<\/li>\n
                • Related substances:<\/strong>\u00a0<1.0% total impurities<\/li>\n
                • Residual solvents:<\/strong>\u00a0Meets ICH Q3C<\/li>\n<\/ul>\n

                  Mass Spectrometry:<\/strong><\/p>\n

                    \n
                  • LC-MS\/MS:<\/strong>\u00a0[M+H]\u207a at m\/z 339.1<\/li>\n
                  • High-Resolution MS:<\/strong>\u00a0Exact mass <3 ppm deviation<\/li>\n<\/ul>\n

                    Nuclear Magnetic Resonance (NMR):<\/strong><\/p>\n

                      \n
                    • \u00b9H NMR (600MHz, DMSO-d\u2086):<\/strong>\u00a0Complete structural assignment<\/li>\n
                    • \u00b9\u2079F NMR:<\/strong>\u00a0Two distinct CF\u2083 signals<\/li>\n
                    • \u00b9\u00b3C NMR (150MHz):<\/strong>\u00a014 distinct carbon signals<\/li>\n
                    • FTIR:<\/strong>\u00a0Amide N-H (3300 cm\u207b\u00b9), C=O (1680 cm\u207b\u00b9), C-F (1120 cm\u207b\u00b9)<\/li>\n<\/ul>\n

                      Physical Testing:<\/strong><\/p>\n

                        \n
                      • Water content:<\/strong>\u00a0<0.3% (Karl Fischer)<\/li>\n
                      • Heavy metals:<\/strong>\u00a0<5 ppm (ICP-MS)<\/li>\n
                      • Specific rotation:<\/strong>\u00a0[\u03b1]\u00b2\u2070D = +8\u00b0 to +12\u00b0<\/li>\n
                      • Particle size:<\/strong>\u00a0Laser diffraction confirmed (20-50\u03bcm)<\/li>\n
                      • Bulk density:<\/strong>\u00a00.4-0.6 g\/cm\u00b3<\/li>\n<\/ul>\n

                        Research Applications & Scientific Significance<\/strong><\/h3>\n

                        LGD-4033 powder<\/strong>\u00a0serves\u00a0expanded research functions<\/strong>:<\/p>\n

                        Formulation Development:<\/strong><\/p>\n

                          \n
                        • Novel delivery systems<\/strong>\u00a0(nanoparticles, liposomes)<\/li>\n
                        • Bioavailability enhancement<\/strong>\u00a0(solubilization techniques)<\/li>\n
                        • Controlled release<\/strong>\u00a0formulations (polymeric matrices)<\/li>\n
                        • Stability studies<\/strong>\u00a0(forced degradation, ICH Q1A)<\/li>\n<\/ul>\n

                          Androgen Receptor Pharmacology:<\/strong><\/p>\n

                            \n
                          • Ultra-high affinity binding<\/strong>\u00a0(sub-nanomolar Ki)<\/li>\n
                          • Crystal structure<\/strong>\u00a0investigations (AR LBD co-crystallization)<\/li>\n
                          • Coactivator recruitment<\/strong>\u00a0(SRC-1, GRIP1, p\/CIP)<\/li>\n
                          • Tissue selectivity profiling<\/strong><\/li>\n<\/ul>\n

                            Musculoskeletal Research:<\/strong><\/p>\n

                              \n
                            • Severe muscle atrophy<\/strong>\u00a0models (cancer cachexia, COPD)<\/li>\n
                            • Hip fracture recovery<\/strong>\u00a0(elderly populations)<\/li>\n
                            • Glucocorticoid-induced myopathy<\/strong><\/li>\n
                            • Sarcopenia<\/strong>\u00a0interventions<\/li>\n<\/ul>\n

                              Comparative SARM Research:<\/strong><\/p>\n

                                \n
                              • Potency comparisons<\/strong>\u00a0(LGD-4033 vs. MK-2866 vs. RAD-140)<\/li>\n
                              • Structure-activity relationships<\/strong><\/li>\n
                              • Selectivity profiling<\/strong>\u00a0(prostate vs. muscle ratios)<\/li>\n
                              • Combination studies<\/strong><\/li>\n<\/ul>\n

                                Global Distribution & Discrete Procurement<\/strong><\/h3>\n

                                BioSynLab provides\u00a0secure, compliant distribution<\/strong>:<\/p>\n

                                Packaging Specifications:<\/strong><\/p>\n

                                  \n
                                • Primary:<\/strong>\u00a0Amber Type I borosilicate glass (5-100mL)<\/li>\n
                                • Secondary:<\/strong>\u00a0Argon-flushed\u00a0aluminized barrier pouch<\/strong><\/li>\n
                                • Tertiary:<\/strong>\u00a0Discrete unmarked shipping containers<\/strong><\/li>\n<\/ul>\n

                                  Shipping Options:<\/strong><\/p>\n

                                    \n
                                  • Standard:<\/strong>\u00a0Ambient temperature, 5-7 days<\/li>\n
                                  • Refrigerated:<\/strong>\u00a02-8\u00b0C for extended stability<\/li>\n
                                  • Express:<\/strong>\u00a0Tracked courier, 2-3 days<\/li>\n
                                  • Discrete:<\/strong>\u00a0No product identifiers, generic return addresses<\/li>\n<\/ul>\n

                                    Bulk Orders:<\/strong><\/p>\n

                                      \n
                                    • Kilogram-scale:<\/strong>\u00a0Available for\u00a0institutional programs<\/strong><\/li>\n
                                    • Batch consistency:<\/strong>\u00a0Inter-batch RSD <2%<\/li>\n
                                    • Custom synthesis:<\/strong>\u00a0Available upon request<\/li>\n<\/ul>\n

                                      Service Coverage:<\/strong><\/p>\n

                                      United Kingdom:<\/strong>\u00a0London, Manchester, Birmingham, Leeds, Glasgow, Liverpool, Sheffield, Bristol, Edinburgh, Cardiff, Belfast, Nottingham, Leicester.<\/p>\n

                                      European Union:<\/strong>\u00a0Berlin, Hamburg, Munich, Cologne, Frankfurt, Amsterdam, Rotterdam, Paris, Lyon, Barcelona, Madrid, Rome, Milan, Vienna, Brussels, Prague, Warsaw.<\/p>\n

                                      North America:<\/strong>\u00a0New York, Los Angeles, Chicago, Houston, Philadelphia, San Antonio, San Diego, Dallas, San Jose, Austin, Toronto, Vancouver.<\/p>\n","protected":false},"excerpt":{"rendered":"

                                      LGD-4033 Powder (Ligandrol) – Industrial Grade Bulk Supply   Product Details Table   Attribute Specification Brand BioSynLab Research Compounds Product Name LGD-4033 (Ligandrol) Synonyms Ligandrol, VK5211, Anabolicum CAS Number 1165910-22-4 Molecular Formula C\u2081\u2084H\u2081\u2082F\u2086N\u2082O Molecular Weight 338.25 g\/mol Chemical Class Selective Androgen Receptor Modulator (SARM) Purity \u226599.0% (HPLC Verified) Appearance White to Off-White Crystalline Powder Form […]<\/p>\n","protected":false},"featured_media":563,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[2275,2237],"product_tag":[16395,2692,16396,16397,16398,16399,16400,16401,16402,16403,16404,16405,16406,16407,16408,16409,16410,16411,16412,16413,16414,16415,16416,16417,16418,16419,16420,16421,16422,16423,16424,16425,16426,16393],"class_list":["post-533","product","type-product","status-publish","has-post-thumbnail","product_cat-muscle-growth-bulking","product_cat-sarms-next-lvl-muscle","product_tag-androgene-rezeptor-modulatoren-kaufen","product_tag-buy-lgd-4033-powder","product_tag-buy-ligandrol-online--german-lgd-4033-pulver-kaufen","product_tag-fornitore-lgd-4033-laboratorio","product_tag-fournisseur-sarms-france","product_tag-high-purity-ligandrol-powder","product_tag-lab-grade-sarms-for-sale","product_tag-lgd-4033-for-research","product_tag-ligandrol-for-lab-use","product_tag-ligandrol-forschung-deutschland","product_tag-ligandrol-groshandel--french-acheter-poudre-lgd-4033","product_tag-ligandrol-laboratoire-france","product_tag-ligandrol-onderzoekschemicalien--polish-kupic-lgd-4033-proszek","product_tag-ligandrol-para-investigacion","product_tag-ligandrol-sarms-polska","product_tag-ligandrol","product_tag-prodotti-chimici-sarms--dutch-lgd-4033-poeder-kopen","product_tag-produits-chimiques-ligandrol--spanish-comprar-lgd-4033-polvo","product_tag-proveedor-sarms-espana","product_tag-purchase-sarms-europe","product_tag-sarms-laboratoriumleverancier","product_tag-sarms-laborchemikalien","product_tag-sarms-powder-bulk-supplier","product_tag-sarms-quimicos-analiticos--italian-comprare-polvere-ligandrol","product_tag-sarms-research-chemicals-online","product_tag-sarms-ricerca-italia","product_tag-sarms-substances-de-recherche","product_tag-sarms-supplier-uk","product_tag-sarms---korean-lgd-4033--","product_tag-sarms","product_tag-substancje-do-badan-sarms--japanese-lgd-4033--","product_tag-16425","product_tag----simplified-chinese-lgd-4033","product_tag--sarms-","first","instock","shipping-taxable","purchasable","product-type-simple"],"yoast_head":"\nBuy LGD-4033 Powder (Ligandrol) \u2013 SARMs for Lab Research<\/title>\n<meta name=\"description\" content=\"Buy LGD-4033 Ligandrol powder online at BioSynLab. \u226599% purity SARM, lab-tested. Discrete shipping USA\/UK\/Europe. COA verified. Research supply.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.biosynlab.com\/product\/lgd-4033-powder-ligandrol\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Buy LGD-4033 Powder (Ligandrol) \u2013 SARMs for Lab Research\" \/>\n<meta property=\"og:description\" content=\"Buy LGD-4033 Ligandrol powder online at BioSynLab. \u226599% purity SARM, lab-tested. Discrete shipping USA\/UK\/Europe. COA verified. Research supply.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.biosynlab.com\/product\/lgd-4033-powder-ligandrol\/\" \/>\n<meta property=\"og:site_name\" content=\"Biosynlab.com\" \/>\n<meta property=\"article:modified_time\" content=\"2026-06-23T03:11:09+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.biosynlab.com\/wp-content\/uploads\/2026\/06\/LGD-4033-Powder-Ligandrol.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"500\" \/>\n\t<meta property=\"og:image:height\" content=\"500\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.biosynlab.com\\\/product\\\/lgd-4033-powder-ligandrol\\\/\",\"url\":\"https:\\\/\\\/www.biosynlab.com\\\/product\\\/lgd-4033-powder-ligandrol\\\/\",\"name\":\"Buy LGD-4033 Powder (Ligandrol) \u2013 SARMs for Lab Research\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.biosynlab.com\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.biosynlab.com\\\/product\\\/lgd-4033-powder-ligandrol\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.biosynlab.com\\\/product\\\/lgd-4033-powder-ligandrol\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.biosynlab.com\\\/wp-content\\\/uploads\\\/2026\\\/06\\\/LGD-4033-Powder-Ligandrol.jpg\",\"datePublished\":\"2026-06-07T23:41:36+00:00\",\"dateModified\":\"2026-06-23T03:11:09+00:00\",\"description\":\"Buy LGD-4033 Ligandrol powder online at BioSynLab. \u226599% purity SARM, lab-tested. 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