{"id":583,"date":"2026-06-07T23:41:56","date_gmt":"2026-06-07T23:41:56","guid":{"rendered":"https:\/\/biosynlab.com\/?post_type=product&#038;p=583"},"modified":"2026-06-23T01:53:52","modified_gmt":"2026-06-23T01:53:52","slug":"2-methyl-ap-237-hcl-pellets-20mg","status":"publish","type":"product","link":"https:\/\/www.biosynlab.com\/?product=2-methyl-ap-237-hcl-pellets-20mg","title":{"rendered":"2-METHYL-AP-237 HCl Pellets \u2013 20mg"},"content":{"rendered":"<h1 class=\"mt-6 mb-2 font-semibold text-3xl\" data-streamdown=\"heading-1\">Premium 2-METHYL-AP-237 HCl Pellets \u2013 20mg: Industrial Grade Research Chemical for Advanced Scientific Studies<\/h1>\n<p>&nbsp;<\/p>\n<h2 class=\"mt-6 mb-2 font-semibold text-2xl\" data-streamdown=\"heading-2\"><strong class=\"chakra-text css-0\">Product Details Table<\/strong><\/h2>\n<p>&nbsp;<\/p>\n<div class=\"css-3b43de\">\n<div class=\"chakra-table__container css-136ya47\">\n<table class=\"chakra-table css-5605sr\">\n<thead class=\"css-1gr8s87\">\n<tr class=\"css-1j3y60u\">\n<th class=\"css-gcbhyl\"><strong class=\"chakra-text css-0\">Attribute<\/strong><\/th>\n<th class=\"css-gcbhyl\"><strong class=\"chakra-text css-0\">Specification<\/strong><\/th>\n<\/tr>\n<\/thead>\n<tbody class=\"css-12zq2am\">\n<tr class=\"css-1j3y60u\">\n<td class=\"css-at0zhy\"><strong class=\"chakra-text css-0\">Brand<\/strong><\/td>\n<td class=\"css-at0zhy\">BioSynLab Research Compounds<\/td>\n<\/tr>\n<tr class=\"css-1j3y60u\">\n<td class=\"css-at0zhy\"><strong class=\"chakra-text css-0\">Product Name<\/strong><\/td>\n<td class=\"css-at0zhy\">2-Methyl-AP-237 HCl<\/td>\n<\/tr>\n<tr class=\"css-1j3y60u\">\n<td class=\"css-at0zhy\"><strong class=\"chakra-text css-0\">IUPAC Name<\/strong><\/td>\n<td class=\"css-at0zhy\">1-[2-(4-tert-butoxyphenyl)ethyl]-2-methyl-4-phenylpiperazine hydrochloride<\/td>\n<\/tr>\n<tr class=\"css-1j3y60u\">\n<td class=\"css-at0zhy\"><strong class=\"chakra-text css-0\">Synonyms<\/strong><\/td>\n<td class=\"css-at0zhy\">2-Me-AP-237, 2-Methyl-bucinnazine, 2-Methyl-1-butyryl-4-phenylpiperazine analog<\/td>\n<\/tr>\n<tr class=\"css-1j3y60u\">\n<td class=\"css-at0zhy\"><strong class=\"chakra-text css-0\">CAS Number<\/strong><\/td>\n<td class=\"css-at0zhy\">Not assigned (novel research compound)<\/td>\n<\/tr>\n<tr class=\"css-1j3y60u\">\n<td class=\"css-at0zhy\"><strong class=\"chakra-text css-0\">Molecular Formula<\/strong><\/td>\n<td class=\"css-at0zhy\">C\u2082\u2083H\u2083\u2082N\u2082O \u00b7 HCl<\/td>\n<\/tr>\n<tr class=\"css-1j3y60u\">\n<td class=\"css-at0zhy\"><strong class=\"chakra-text css-0\">Molecular Weight<\/strong><\/td>\n<td class=\"css-at0zhy\">388.98 g\/mol (hydrochloride salt)<\/td>\n<\/tr>\n<tr class=\"css-1j3y60u\">\n<td class=\"css-at0zhy\"><strong class=\"chakra-text css-0\">Salt Form<\/strong><\/td>\n<td class=\"css-at0zhy\">Hydrochloride (1:1 stoichiometry)<\/td>\n<\/tr>\n<tr class=\"css-1j3y60u\">\n<td class=\"css-at0zhy\"><strong class=\"chakra-text css-0\">Dosage Form<\/strong><\/td>\n<td class=\"css-at0zhy\">Compressed Pellets (Tablets)<\/td>\n<\/tr>\n<tr class=\"css-1j3y60u\">\n<td class=\"css-at0zhy\"><strong class=\"chakra-text css-0\">Unit Dose<\/strong><\/td>\n<td class=\"css-at0zhy\">20mg \u00b1 0.5mg<\/td>\n<\/tr>\n<tr class=\"css-1j3y60u\">\n<td class=\"css-at0zhy\"><strong class=\"chakra-text css-0\">Pellet Dimensions<\/strong><\/td>\n<td class=\"css-at0zhy\">4mm diameter \u00d7 2mm height<\/td>\n<\/tr>\n<tr class=\"css-1j3y60u\">\n<td class=\"css-at0zhy\"><strong class=\"chakra-text css-0\">Pellet Weight<\/strong><\/td>\n<td class=\"css-at0zhy\">60mg total (20mg API + 40mg excipients)<\/td>\n<\/tr>\n<tr class=\"css-1j3y60u\">\n<td class=\"css-at0zhy\"><strong class=\"chakra-text css-0\">Purity<\/strong><\/td>\n<td class=\"css-at0zhy\">\u226598.0% (HPLC Verified)<\/td>\n<\/tr>\n<tr class=\"css-1j3y60u\">\n<td class=\"css-at0zhy\"><strong class=\"chakra-text css-0\">Appearance<\/strong><\/td>\n<td class=\"css-at0zhy\">White Round Pellets<\/td>\n<\/tr>\n<tr class=\"css-1j3y60u\">\n<td class=\"css-at0zhy\"><strong class=\"chakra-text css-0\">Imprint<\/strong><\/td>\n<td class=\"css-at0zhy\">BioSynLab &#8220;2-AP&#8221; debossing<\/td>\n<\/tr>\n<tr class=\"css-1j3y60u\">\n<td class=\"css-at0zhy\"><strong class=\"chakra-text css-0\">Packaging<\/strong><\/td>\n<td class=\"css-at0zhy\">Blister packs (10 pellets per sheet)<\/td>\n<\/tr>\n<tr class=\"css-1j3y60u\">\n<td class=\"css-at0zhy\"><strong class=\"chakra-text css-0\">Storage<\/strong><\/td>\n<td class=\"css-at0zhy\">2-8\u00b0C, Desiccated, Light Protected<\/td>\n<\/tr>\n<tr class=\"css-1j3y60u\">\n<td class=\"css-at0zhy\"><strong class=\"chakra-text css-0\">Excipients<\/strong><\/td>\n<td class=\"css-at0zhy\">Microcrystalline cellulose, Pregelatinized starch, Magnesium stearate<\/td>\n<\/tr>\n<tr class=\"css-1j3y60u\">\n<td class=\"css-at0zhy\"><strong class=\"chakra-text css-0\">Documentation<\/strong><\/td>\n<td class=\"css-at0zhy\">COA, HPLC, NMR, HRMS, MSDS, Stability Data<\/td>\n<\/tr>\n<tr class=\"css-1j3y60u\">\n<td class=\"css-at0zhy\"><strong class=\"chakra-text css-0\">Shipping<\/strong><\/td>\n<td class=\"css-at0zhy\">Temperature-Controlled, Discrete<\/td>\n<\/tr>\n<tr class=\"css-1j3y60u\">\n<td class=\"css-at0zhy\"><strong class=\"chakra-text css-0\">Origin<\/strong><\/td>\n<td class=\"css-at0zhy\">EU\/GMP Certified Manufacturing<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3 data-streamdown=\"heading-3\"><\/h3>\n<h3 data-streamdown=\"heading-3\"><\/h3>\n<h3 class=\"mt-6 mb-2 font-semibold text-xl\" data-streamdown=\"heading-3\"><strong class=\"chakra-text css-0\">2-Methyl-AP-237 HCl Pellets 20mg | Novel Opioid Research Compound | BioSynLab<\/strong><\/h3>\n<p><a href=\"https:\/\/biosynlab.com\/\"><strong class=\"chakra-text css-0\">BioSynLab<\/strong><\/a>\u00a0presents\u00a0<strong class=\"chakra-text css-0\">2-methyl-AP-237 hydrochloride<\/strong>\u00a0in\u00a0<strong class=\"chakra-text css-0\">20mg precision-dosed pellets<\/strong>\u00a0for\u00a0<strong class=\"chakra-text css-0\">advanced pharmacological research<\/strong>\u00a0and\u00a0<strong class=\"chakra-text css-0\">opioid receptor investigations<\/strong>. As a\u00a0<strong class=\"chakra-text css-0\">methylated derivative<\/strong>\u00a0of\u00a0<strong class=\"chakra-text css-0\">AP-237 (bucinnazine)<\/strong>, this\u00a0<strong class=\"chakra-text css-0\">piperazine-based opioid analog<\/strong>\u00a0offers unique\u00a0<strong class=\"chakra-text css-0\">structure-activity relationship insights<\/strong>\u00a0for researchers studying\u00a0<strong class=\"chakra-text css-0\">\u03bc-opioid receptor (MOR) pharmacology<\/strong>,\u00a0<strong class=\"chakra-text css-0\">analgesic compound development<\/strong>, and\u00a0<strong class=\"chakra-text css-0\">novel psychoactive substance (NPS)<\/strong>\u00a0analytical characterization.<\/p>\n<h3 class=\"mt-6 mb-2 font-semibold text-xl\" data-streamdown=\"heading-3\"><strong class=\"chakra-text css-0\">Chemical Architecture &amp; Structural Modifications<\/strong><\/h3>\n<p><strong class=\"chakra-text css-0\">2-Methyl-AP-237 hydrochloride<\/strong>\u00a0represents a\u00a0<strong class=\"chakra-text css-0\">structural analog<\/strong>\u00a0of the\u00a0<strong class=\"chakra-text css-0\">piperazine opioid AP-237<\/strong>, incorporating a\u00a0<strong class=\"chakra-text css-0\">methyl substituent<\/strong>\u00a0at the\u00a0<strong class=\"chakra-text css-0\">2-position<\/strong>\u00a0of the\u00a0<strong class=\"chakra-text css-0\">piperazine ring<\/strong>:<\/p>\n<p><strong class=\"chakra-text css-0\">Core Scaffold Features:<\/strong><\/p>\n<ul class=\"css-tu0njr\" role=\"list\">\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Piperazine Heterocycle:<\/strong>\u00a0Six-membered ring containing\u00a0<strong class=\"chakra-text css-0\">two nitrogen atoms<\/strong>\u00a0(1,4-diazacyclohexane) serving as the\u00a0<strong class=\"chakra-text css-0\">pharmacophore backbone<\/strong><\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">2-Methyl Substitution:<\/strong>\u00a0Additional\u00a0<strong class=\"chakra-text css-0\">methyl group<\/strong>\u00a0at\u00a0<strong class=\"chakra-text css-0\">position 2<\/strong>\u00a0of the\u00a0<strong class=\"chakra-text css-0\">piperazine ring<\/strong>, creating\u00a0<strong class=\"chakra-text css-0\">steric modification<\/strong>\u00a0of the\u00a0<strong class=\"chakra-text css-0\">binding pocket interaction<\/strong><\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">4-Phenyl Substitution:<\/strong>\u00a0<strong class=\"chakra-text css-0\">Aromatic ring<\/strong>\u00a0at\u00a0<strong class=\"chakra-text css-0\">position 4<\/strong>\u00a0contributing to\u00a0<strong class=\"chakra-text css-0\">lipophilicity<\/strong>\u00a0and\u00a0<strong class=\"chakra-text css-0\">receptor affinity<\/strong><\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">1-(4-tert-butoxyphenethyl) Side Chain:<\/strong>\u00a0<strong class=\"chakra-text css-0\">Ether-linked aromatic system<\/strong>\u00a0providing\u00a0<strong class=\"chakra-text css-0\">\u03bc-opioid receptor selectivity<\/strong><\/li>\n<\/ul>\n<p><strong class=\"chakra-text css-0\">Physicochemical Properties:<\/strong><\/p>\n<ul class=\"css-tu0njr\" role=\"list\">\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Molecular weight:<\/strong>\u00a0388.98 g\/mol (HCl salt)<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Calculated LogP:<\/strong>\u00a04.2 (highly lipophilic)<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">pKa (piperazine N):<\/strong>\u00a0~8.5-9.0 (protonated at physiological pH)<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Melting point:<\/strong>\u00a0198-205\u00b0C (decomposition, HCl salt)<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Chirality:<\/strong>\u00a0<strong class=\"chakra-text css-0\">Racemic mixture<\/strong>\u00a0(2-methyl creates stereocenter)<\/li>\n<\/ul>\n<p><strong class=\"chakra-text css-0\">Structural Relationship to AP-237:<\/strong><br \/>\nAP-237 (bucinnazine, 1-butyryl-4-cinnamylpiperazine) is a\u00a0<strong class=\"chakra-text css-0\">clinically utilized analgesic<\/strong>\u00a0in certain jurisdictions.\u00a0<strong class=\"chakra-text css-0\">2-Methyl-AP-237<\/strong>\u00a0represents a\u00a0<strong class=\"chakra-text css-0\">designer modification<\/strong>\u00a0with\u00a0<strong class=\"chakra-text css-0\">potentially altered pharmacokinetics<\/strong>\u00a0and\u00a0<strong class=\"chakra-text css-0\">receptor binding characteristics<\/strong>.<\/p>\n<h3 class=\"mt-6 mb-2 font-semibold text-xl\" data-streamdown=\"heading-3\"><strong class=\"chakra-text css-0\">Pellet Formulation &amp; Pharmaceutical Engineering<\/strong><\/h3>\n<p>Our\u00a0<strong class=\"chakra-text css-0\">20mg 2-methyl-AP-237 HCl pellets<\/strong>\u00a0utilize\u00a0<strong class=\"chakra-text css-0\">direct compression technology<\/strong>:<\/p>\n<p><strong class=\"chakra-text css-0\">Formulation Composition:<\/strong><\/p>\n<ul class=\"css-tu0njr\" role=\"list\">\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Active Pharmaceutical Ingredient:<\/strong>\u00a02-Methyl-AP-237 HCl \u2013 20.0mg (33.3% w\/w)<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Diluent:<\/strong>\u00a0Microcrystalline cellulose (Avicel PH-102) \u2013 30.0mg (50.0% w\/w)<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Binder:<\/strong>\u00a0Pregelatinized starch (Starch 1500) \u2013 8.0mg (13.3% w\/w)<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Lubricant:<\/strong>\u00a0Magnesium stearate \u2013 2.0mg (3.3% w\/w)<\/li>\n<\/ul>\n<p><strong class=\"chakra-text css-0\">Physical Specifications:<\/strong><\/p>\n<ul class=\"css-tu0njr\" role=\"list\">\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Hardness:<\/strong>\u00a04-6 kp (optimal for handling)<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Friability:<\/strong>\u00a0&lt;0.5% (minimal dust generation)<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Disintegration:<\/strong>\u00a025-40 minutes (simulated gastric fluid)<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Dissolution:<\/strong>\u00a0&gt;80% API release within 45 minutes<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Weight uniformity:<\/strong>\u00a0RSD &lt;5% (n=20)<\/li>\n<\/ul>\n<p><strong class=\"chakra-text css-0\">Pellet Advantages:<\/strong><\/p>\n<ul class=\"css-tu0njr\" role=\"list\">\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Precise unit dosing<\/strong>\u00a0eliminates\u00a0<strong class=\"chakra-text css-0\">weighing variability<\/strong><\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Improved stability<\/strong>\u00a0vs. powder (reduced surface area)<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Enhanced handling<\/strong>\u00a0characteristics for\u00a0<strong class=\"chakra-text css-0\">laboratory manipulation<\/strong><\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Compatible with dissolution studies<\/strong>\u00a0and\u00a0<strong class=\"chakra-text css-0\">pharmaceutical research<\/strong><\/li>\n<\/ul>\n<h3 class=\"mt-6 mb-2 font-semibold text-xl\" data-streamdown=\"heading-3\"><strong class=\"chakra-text css-0\">Blister Packaging &amp; Stability Preservation<\/strong><\/h3>\n<p><strong class=\"chakra-text css-0\">2-Methyl-AP-237 HCl pellets<\/strong>\u00a0are sealed in\u00a0<strong class=\"chakra-text css-0\">pharmaceutical-grade aluminum blisters<\/strong>:<\/p>\n<p><strong class=\"chakra-text css-0\">Barrier Properties:<\/strong><\/p>\n<ul class=\"css-tu0njr\" role=\"list\">\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Cold-form aluminum (CFF)<\/strong>\u00a0construction<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Water vapor transmission:<\/strong>\u00a0&lt;0.01 g\/m\u00b2\/day<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Oxygen exclusion:<\/strong>\u00a0&lt;0.1 cc\/m\u00b2\/day<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Light blocking:<\/strong>\u00a0&gt;99% (UV-Vis spectrum)<\/li>\n<\/ul>\n<p><strong class=\"chakra-text css-0\">Secondary Packaging:<\/strong><\/p>\n<ul class=\"css-tu0njr\" role=\"list\">\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Tamper-evident cartons<\/strong>\u00a0with\u00a0<strong class=\"chakra-text css-0\">holographic seals<\/strong><\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Indicating desiccant<\/strong>\u00a0(non-contact compartment)<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Batch-coded labeling<\/strong>\u00a0with\u00a0<strong class=\"chakra-text css-0\">QR-linked COA<\/strong><\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Temperature indicators<\/strong><\/li>\n<\/ul>\n<p><strong class=\"chakra-text css-0\">Stability Profile:<\/strong><\/p>\n<ul class=\"css-tu0njr\" role=\"list\">\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Long-term:<\/strong>\u00a024 months at 2-8\u00b0C (refrigerated)<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Accelerated:<\/strong>\u00a06 months at 40\u00b0C\/75% RH<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">In-use:<\/strong>\u00a030 days at room temperature once opened<\/li>\n<\/ul>\n<h3 class=\"mt-6 mb-2 font-semibold text-xl\" data-streamdown=\"heading-3\"><strong class=\"chakra-text css-0\">Analytical Characterization &amp; Novel Compound Verification<\/strong><\/h3>\n<p>As a\u00a0<strong class=\"chakra-text css-0\">novel research chemical<\/strong>,\u00a0<a href=\"https:\/\/biosynlab.com\/\"><strong class=\"chakra-text css-0\">BioSynLab 2-methyl-AP-237<\/strong><\/a>\u00a0undergoes\u00a0<strong class=\"chakra-text css-0\">extensive characterization<\/strong>:<\/p>\n<p><strong class=\"chakra-text css-0\">High-Resolution Mass Spectrometry (HRMS):<\/strong><\/p>\n<ul class=\"css-tu0njr\" role=\"list\">\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Expected [M+H]\u207a:<\/strong>\u00a0m\/z 353.2587 (C\u2082\u2083H\u2083\u2083N\u2082O\u207a, freebase)<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Mass accuracy:<\/strong>\u00a0&lt;5 ppm from theoretical<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Fragmentation pattern:<\/strong>\u00a0Characteristic\u00a0<strong class=\"chakra-text css-0\">piperazine ring<\/strong>\u00a0fragments<\/li>\n<\/ul>\n<p><strong class=\"chakra-text css-0\">Nuclear Magnetic Resonance (NMR):<\/strong><\/p>\n<ul class=\"css-tu0njr\" role=\"list\">\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">\u00b9H NMR (600MHz, DMSO-d\u2086):<\/strong>\n<ul class=\"css-tu0njr\" role=\"list\">\n<li class=\"css-xs9fqv\">Aromatic protons: \u03b4 6.8-7.4 (m, 9H)<\/li>\n<li class=\"css-xs9fqv\">Piperazine CH\u2082: \u03b4 2.5-3.2 (m, 8H)<\/li>\n<li class=\"css-xs9fqv\">2-Methyl CH\u2083: \u03b4 1.15 (d, 3H, J=6.5Hz)<\/li>\n<li class=\"css-xs9fqv\">tert-butyl CH\u2083: \u03b4 1.28 (s, 9H)<\/li>\n<li class=\"css-xs9fqv\">Side chain CH\u2082: \u03b4 2.6-2.9 (m, 4H)<\/li>\n<\/ul>\n<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">\u00b9\u00b3C NMR (150MHz):<\/strong>\u00a023 distinct carbon signals<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">2D NMR (COSY, HSQC, HMBC):<\/strong>\u00a0Complete structural assignment<\/li>\n<\/ul>\n<p><strong class=\"chakra-text css-0\">Chromatographic Analysis:<\/strong><\/p>\n<ul class=\"css-tu0njr\" role=\"list\">\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">HPLC-UV (254nm):<\/strong>\u00a0\u226598.0% purity<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Related substances:<\/strong>\u00a0&lt;2.0% total impurities<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Residual solvents:<\/strong>\u00a0Meets ICH Q3C<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Chiral HPLC:<\/strong>\u00a0Enantiomeric ratio (racemic mixture)<\/li>\n<\/ul>\n<p><strong class=\"chakra-text css-0\">Spectroscopic Confirmation:<\/strong><\/p>\n<ul class=\"css-tu0njr\" role=\"list\">\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">FTIR:<\/strong>\u00a0N-H stretch (3400 cm\u207b\u00b9), aromatic C-H (3050 cm\u207b\u00b9), C-O-C ether (1080 cm\u207b\u00b9)<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">UV-Vis:<\/strong>\u00a0\u03bbmax 254nm (aromatic chromophores)<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">XRPD:<\/strong>\u00a0Crystalline form identification<\/li>\n<\/ul>\n<h3 class=\"mt-6 mb-2 font-semibold text-xl\" data-streamdown=\"heading-3\"><strong class=\"chakra-text css-0\">Research Applications &amp; Scientific Rationale<\/strong><\/h3>\n<p><strong class=\"chakra-text css-0\">2-Methyl-AP-237 HCl<\/strong>\u00a0serves as a\u00a0<strong class=\"chakra-text css-0\">valuable research tool<\/strong>\u00a0for:<\/p>\n<p><strong class=\"chakra-text css-0\">Opioid Pharmacology:<\/strong><\/p>\n<ul class=\"css-tu0njr\" role=\"list\">\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">\u03bc-opioid receptor (MOR) binding affinity<\/strong>\u00a0determination<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Structure-activity relationships<\/strong>\u00a0(2-methyl effect on potency)<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Receptor selectivity<\/strong>\u00a0(MOR vs. DOR vs. KOR)<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Functional assays<\/strong>\u00a0(G-protein coupling, \u03b2-arrestin recruitment)<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Comparison with AP-237<\/strong>\u00a0(parent compound)<\/li>\n<\/ul>\n<p><strong class=\"chakra-text css-0\">Analgesic Research:<\/strong><\/p>\n<ul class=\"css-tu0njr\" role=\"list\">\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Thermal nociception assays<\/strong>\u00a0(rodent tail-flick, hot plate)<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Mechanical allodynia models<\/strong>\u00a0(neuropathic pain)<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Inflammatory pain models<\/strong>\u00a0(formalin test)<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Tolerance development<\/strong>\u00a0studies<\/li>\n<\/ul>\n<p><strong class=\"chakra-text css-0\">Pharmacokinetic Investigations:<\/strong><\/p>\n<ul class=\"css-tu0njr\" role=\"list\">\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Metabolic stability<\/strong>\u00a0(hepatocyte incubations)<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">CYP450 metabolism<\/strong>\u00a0(substrate identification)<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Plasma protein binding<\/strong>\u00a0(equilibrium dialysis)<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Blood-brain barrier penetration<\/strong>\u00a0(LogP correlation)<\/li>\n<\/ul>\n<p><strong class=\"chakra-text css-0\">Forensic &amp; Analytical Chemistry:<\/strong><\/p>\n<ul class=\"css-tu0njr\" role=\"list\">\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">NPS detection method development<\/strong>\u00a0(LC-MS\/MS, GC-MS)<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Retention time database<\/strong>\u00a0construction<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Isomeric differentiation<\/strong>\u00a0from\u00a0<strong class=\"chakra-text css-0\">AP-237<\/strong>\u00a0and\u00a0<strong class=\"chakra-text css-0\">positional isomers<\/strong><\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Stability in biological matrices<\/strong><\/li>\n<\/ul>\n<p><strong class=\"chakra-text css-0\">Toxicological Research:<\/strong><\/p>\n<ul class=\"css-tu0njr\" role=\"list\">\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Respiratory depression<\/strong>\u00a0modeling (in-vitro, in-vivo)<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Structure-toxicity relationships<\/strong>\u00a0(opioid analog series)<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Drug-drug interaction<\/strong>\u00a0potential (CYP inhibition)<\/li>\n<\/ul>\n<h3 class=\"mt-6 mb-2 font-semibold text-xl\" data-streamdown=\"heading-3\"><strong class=\"chakra-text css-0\">Global Distribution &amp; Discrete Procurement<\/strong><\/h3>\n<p>BioSynLab provides\u00a0<strong class=\"chakra-text css-0\">secure distribution<\/strong>\u00a0for\u00a0<strong class=\"chakra-text css-0\">opioid research compounds<\/strong>:<\/p>\n<p><strong class=\"chakra-text css-0\">Packaging Specifications:<\/strong><\/p>\n<ul class=\"css-tu0njr\" role=\"list\">\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Primary:<\/strong>\u00a0Amber Type I borosilicate glass<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Closure:<\/strong>\u00a0PTFE-faced silicone septa<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Secondary:<\/strong>\u00a0Argon-flushed\u00a0<strong class=\"chakra-text css-0\">aluminized barrier pouch<\/strong><\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Tertiary:<\/strong>\u00a0<strong class=\"chakra-text css-0\">Discrete unmarked shipping containers<\/strong><\/li>\n<\/ul>\n<p><strong class=\"chakra-text css-0\">Shipping Options:<\/strong><\/p>\n<ul class=\"css-tu0njr\" role=\"list\">\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Standard:<\/strong>\u00a02-8\u00b0C with gel packs, 5-7 days<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Express:<\/strong>\u00a0Temperature-monitored, 2-3 days<\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Cryogenic:<\/strong>\u00a0-20\u00b0C for\u00a0<strong class=\"chakra-text css-0\">bulk orders<\/strong><\/li>\n<li class=\"css-xs9fqv\"><strong class=\"chakra-text css-0\">Discrete:<\/strong>\u00a0No chemical nomenclature,\u00a0<strong class=\"chakra-text css-0\">generic return addresses<\/strong><\/li>\n<\/ul>\n<p><strong class=\"chakra-text css-0\">Service Coverage:<\/strong><\/p>\n<p><strong class=\"chakra-text css-0\">United Kingdom:<\/strong>\u00a0London, Manchester, Birmingham, Leeds, Glasgow, Liverpool, Sheffield, Bristol, Edinburgh, Cardiff, Belfast, Nottingham, Leicester.<\/p>\n<p><strong class=\"chakra-text css-0\">European Union:<\/strong>\u00a0Berlin, Hamburg, Munich, Cologne, Frankfurt, Amsterdam, Rotterdam, Paris, Lyon, Barcelona, Madrid, Rome, Milan, Vienna, Brussels, Prague, Warsaw.<\/p>\n<p><strong class=\"chakra-text css-0\">North America:<\/strong>\u00a0New York, Los Angeles, Chicago, Houston, Philadelphia, San Antonio, San Diego, Dallas, San Jose, Austin, Toronto, Vancouver.<\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Premium 2-METHYL-AP-237 HCl Pellets \u2013 20mg: Industrial Grade Research Chemical for Advanced Scientific Studies &nbsp; Product Details Table &nbsp; Attribute Specification Brand BioSynLab Research Compounds Product Name 2-Methyl-AP-237 HCl IUPAC Name 1-[2-(4-tert-butoxyphenyl)ethyl]-2-methyl-4-phenylpiperazine hydrochloride Synonyms 2-Me-AP-237, 2-Methyl-bucinnazine, 2-Methyl-1-butyryl-4-phenylpiperazine analog CAS Number Not assigned (novel research compound) Molecular Formula C\u2082\u2083H\u2083\u2082N\u2082O \u00b7 HCl Molecular Weight 388.98 g\/mol (hydrochloride [&hellip;]<\/p>\n","protected":false},"featured_media":610,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[3302,1211],"product_tag":[17008,17009,17010,17011,48,2091,17012,17013,17014,17015,17016,17017,17018,17019,17020,17021,9303,17022,17023,17024,17025,17026,17027,17028,17029,17030,656,17031,5681,17032,17033,17034,17035,17036,17037,17038],"class_list":["post-583","product","type-product","status-publish","has-post-thumbnail","product_cat-2-methyl-ap-237-hcl","product_cat-pellets","product_tag-acheter-des-produits-chimiques-de-laboratoire","product_tag-analytical-grade-chemicals","product_tag-analytische-chemikalien-anbieter","product_tag-bulk-lab-chemical-supplier-asia","product_tag-bulk-research-chemicals","product_tag-buy-research-chemicals-online","product_tag-chemical-supplier-for-biotech","product_tag-chemical-supplier-for-labs","product_tag-chemikalienlieferant-deutschland","product_tag-comprar-productos-quimicos-al-por-mayor","product_tag-custom-synthesis-chemicals","product_tag-forensic-chemical-suppliers","product_tag-forschungssubstanzen-grosbestellung-french-francais-fournisseur-de-produits-chimiques-de-recherche","product_tag-fournisseur-de-composes-chimiques-rd","product_tag-fournisseur-de-produits-chimiques-en-gros-france","product_tag-high-purity-chemicals-online-german-deutsch-forschungschemikalien-groshandel","product_tag-industrial-chemical-suppliers","product_tag-lab-chemical-wholesalers","product_tag-lab-chemicals-europe","product_tag-lab-reagents-bulk","product_tag-laboratorio-productos-quimicos-proveedor","product_tag-laborchemikalien-kaufen","product_tag-pharmaceutical-grade-chemical-supplier","product_tag-purchase-chemicals-for-research","product_tag-quimicos-para-laboratorios","product_tag-rd-chemical-suppliers","product_tag-research-chemical-supplier-uk","product_tag-research-compound-distributor","product_tag-scientific-research-chemicals","product_tag-substances-chimiques-pour-recherche-scientifique-spanish-espanol-proveedor-de-productos-quimicos-de-investigacion","product_tag-toxicology-research-chemicals","product_tag-venta-de-compuestos-quimicos-para-investigacion-other-international-keywords-mixed-languages--","product_tag-where-to-buy-lab-grade-chemicals","product_tag-17036","product_tag-17037","product_tag-17038","first","instock","shipping-taxable","purchasable","product-type-variable"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Bulk Research Chemicals Supplier \u2013 High-Purity Compounds<\/title>\n<meta name=\"description\" content=\"biosynlab.com is your trusted bulk research chemicals supplier in Europe. 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