{"id":633,"date":"2026-06-07T23:42:11","date_gmt":"2026-06-07T23:42:11","guid":{"rendered":"https:\/\/biosynlab.com\/?post_type=product&p=633"},"modified":"2026-06-22T13:13:27","modified_gmt":"2026-06-22T13:13:27","slug":"5-meo-dmt-powder-fumarate","status":"publish","type":"product","link":"https:\/\/www.biosynlab.com\/?product=5-meo-dmt-powder-fumarate","title":{"rendered":"5-MeO-DMT Powder (Fumarate)"},"content":{"rendered":"

Premium 5-MeO-DMT Fumarate Powder: Industrial Grade Research Chemical<\/h1>\n

 <\/p>\n

Product Details Table<\/strong><\/h2>\n

 <\/p>\n

\n
\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Attribute<\/strong><\/th>\nSpecification<\/strong><\/th>\n<\/tr>\n<\/thead>\n
Brand<\/strong><\/td>\nBioSynLab Research Compounds<\/td>\n<\/tr>\n
Product Name<\/strong><\/td>\n5-MeO-DMT Fumarate<\/td>\n<\/tr>\n
IUPAC Name<\/strong><\/td>\n3-[2-(Dimethylamino)ethyl]-5-methoxyindole fumarate<\/td>\n<\/tr>\n
Synonyms<\/strong><\/td>\n5-Methoxy-DMT, O-methylbufotenin, Toad extract analog<\/td>\n<\/tr>\n
CAS Number<\/strong><\/td>\n96096-55-8 (fumarate salt); 1019-45-0 (freebase)<\/td>\n<\/tr>\n
Molecular Formula<\/strong><\/td>\nC\u2081\u2084H\u2082\u2080N\u2082O \u00b7 C\u2084H\u2084O\u2084<\/td>\n<\/tr>\n
Molecular Weight<\/strong><\/td>\n348.39 g\/mol (salt); 218.29 g\/mol (freebase equivalent)<\/td>\n<\/tr>\n
Salt Form<\/strong><\/td>\nFumarate (1:1 stoichiometry)<\/td>\n<\/tr>\n
Purity<\/strong><\/td>\n\u226599.0% (HPLC Verified)<\/td>\n<\/tr>\n
Appearance<\/strong><\/td>\nWhite to Off-White Crystalline Powder<\/td>\n<\/tr>\n
Form<\/strong><\/td>\nMicronized Crystalline Powder<\/td>\n<\/tr>\n
Particle Size<\/strong><\/td>\n20-60 microns<\/td>\n<\/tr>\n
Storage<\/strong><\/td>\n-20\u00b0C, Desiccated, Argon Atmosphere<\/td>\n<\/tr>\n
Packaging<\/strong><\/td>\nAmber Borosilicate Vials with PTFE Seals<\/td>\n<\/tr>\n
Available Quantities<\/strong><\/td>\n100mg, 250mg, 500mg, 1g, 5g<\/td>\n<\/tr>\n
Documentation<\/strong><\/td>\nCOA, HPLC, NMR, MSDS, Stability Data, Residual Solvent Report<\/td>\n<\/tr>\n
Shipping<\/strong><\/td>\nCryogenic, Temperature-Validated, Discrete<\/td>\n<\/tr>\n
Origin<\/strong><\/td>\nEU\/GMP Certified Synthesis<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

<\/h3>\n

5-MeO-DMT Fumarate Powder | Premium Serotonergic Research Compound | BioSynLab<\/strong><\/h3>\n

BioSynLab<\/strong>\u00a0presents\u00a0pharmaceutical-grade 5-MeO-DMT fumarate<\/strong>\u00a0for\u00a0advanced neuropharmacological research<\/strong>\u00a0and\u00a0comparative tryptamine studies<\/strong>. As the\u00a0N,N-dimethyl analog<\/strong>\u00a0of\u00a05-methoxytryptamine<\/strong><\/a>, this\u00a0substituted indolealkylamine<\/strong>\u00a0serves as a critical\u00a0reference standard<\/strong>\u00a0for investigating\u00a05-HT1A\/5-HT2A receptor pharmacology<\/strong>,\u00a0default mode network disruption<\/strong>, and\u00a0structure-activity relationships<\/strong>\u00a0among\u00a0short-acting psychedelics<\/strong>.<\/p>\n

Chemical Architecture & Salt Form Advantages<\/strong><\/h3>\n

5-Methoxy-N,N-dimethyltryptamine fumarate<\/strong>\u00a0represents the\u00a0hemifumarate salt<\/strong>\u00a0of the\u00a0freebase compound<\/strong>, offering\u00a0enhanced stability<\/strong>\u00a0and\u00a0handling characteristics<\/strong>\u00a0for\u00a0laboratory research<\/strong>:<\/p>\n

Structural Features:<\/strong><\/p>\n

    \n
  • 5-Methoxy Substitution:<\/strong>\u00a0Electron-donating group at\u00a05-position<\/strong>\u00a0enhances\u00a0lipophilicity<\/strong>\u00a0and\u00a0modulates receptor binding<\/strong>\u00a0compared to\u00a0unsubstituted DMT<\/strong><\/li>\n
  • N,N-Dimethyl Substitution:<\/strong>\u00a0Tertiary amine confers\u00a0metabolic resistance<\/strong>\u00a0to\u00a0monoamine oxidase (MAO)<\/strong>\u00a0degradation, though\u00a05-MeO-DMT remains a MAO substrate<\/strong><\/li>\n
  • Fumarate Counterion:<\/strong>\u00a0Dicarboxylic acid salt provides\u00a0crystalline stability<\/strong>,\u00a0reduced hygroscopicity<\/strong>, and\u00a0improved shelf-life<\/strong>\u00a0vs.\u00a0hydrochloride<\/strong>\u00a0or\u00a0freebase forms<\/strong><\/li>\n<\/ul>\n

    Physicochemical Properties:<\/strong><\/p>\n

      \n
    • pKa (indole NH):<\/strong>\u00a0~16.8 (DMSO)<\/li>\n
    • pKa (dimethylamino):<\/strong>\u00a0~8.9 (aqueous)<\/li>\n
    • LogP (calculated):<\/strong>\u00a03.4 (freebase equivalent)<\/li>\n
    • Melting Point:<\/strong>\u00a0178-182\u00b0C (decomposition, fumarate salt)<\/li>\n
    • Chirality:<\/strong>\u00a0Achiral (no stereocenters)<\/li>\n<\/ul>\n

      Fumarate Salt Benefits:<\/strong><\/p>\n

        \n
      • Enhanced oxidative stability<\/strong>\u00a0compared to freebase<\/li>\n
      • Reduced volatility<\/strong>\u00a0(lower inhalation risk during handling)<\/li>\n
      • Improved crystallinity<\/strong>\u00a0for\u00a0X-ray diffraction studies<\/strong><\/li>\n
      • Compatible with aqueous formulations<\/strong>\u00a0at physiological pH<\/li>\n<\/ul>\n

        Analytical Characterization & Quality Verification<\/strong><\/h3>\n

        Each\u00a0BioSynLab 5-MeO-DMT fumarate<\/strong>\u00a0batch undergoes\u00a0comprehensive analytical profiling<\/strong>:<\/p>\n

        Chromatographic Analysis:<\/strong><\/p>\n

          \n
        • HPLC-UV (280nm):<\/strong>\u00a0\u226599.0% purity by area normalization<\/li>\n
        • Chiral HPLC:<\/strong>\u00a0Confirms absence of\u00a0chiral impurities<\/strong>\u00a0(achiral compound)<\/li>\n
        • Ion Chromatography:<\/strong>\u00a0Fumarate counterion stoichiometry confirmation (1:1 ratio)<\/li>\n
        • Residual solvents:<\/strong>\u00a0Meets ICH Q3C (methanol, ethanol, acetonitrile, ethyl acetate)<\/li>\n<\/ul>\n

          Spectroscopic Confirmation:<\/strong><\/p>\n

            \n
          • \u00b9H NMR (500MHz, DMSO-d\u2086):<\/strong>\n
              \n
            • Indole N-H: \u03b4 10.85 (br s, 1H)<\/li>\n
            • Aromatic H-4, H-6, H-7: \u03b4 6.95-7.25 (m, 3H)<\/li>\n
            • Methoxy: \u03b4 3.78 (s, 3H, -OCH\u2083)<\/li>\n
            • N-CH\u2082: \u03b4 3.08 (t, 2H, J=7.2Hz)<\/li>\n
            • CH\u2082-CH\u2082: \u03b4 2.82 (t, 2H, J=7.2Hz)<\/li>\n
            • N(CH\u2083)\u2082: \u03b4 2.32 (s, 6H)<\/li>\n
            • Fumarate H: \u03b4 6.52 (s, 2H, olefinic)<\/li>\n<\/ul>\n<\/li>\n
            • \u00b9\u00b3C NMR (125MHz):<\/strong>\u00a019 distinct carbon signals<\/li>\n
            • FTIR:<\/strong>\u00a0Fumarate C=O (1680, 1550 cm\u207b\u00b9), indole N-H (3400 cm\u207b\u00b9), C-O-C (1080 cm\u207b\u00b9)<\/li>\n
            • UV-Vis:<\/strong>\u00a0\u03bbmax 218nm, 275nm, 280nm<\/li>\n
            • LC-MS\/MS:<\/strong>\u00a0[M+H]\u207a at m\/z 219.1 (freebase), fragmentation pattern matching reference<\/li>\n<\/ul>\n

              Physical Testing:<\/strong><\/p>\n

                \n
              • Water content:<\/strong>\u00a0<0.5% (Karl Fischer)<\/li>\n
              • Heavy metals:<\/strong>\u00a0<10 ppm (ICP-MS)<\/li>\n
              • Sulfated ash:<\/strong>\u00a0<0.1%<\/li>\n
              • Specific rotation:<\/strong>\u00a0N\/A (achiral)<\/li>\n
              • X-ray powder diffraction (XRPD):<\/strong>\u00a0Crystalline form confirmation<\/li>\n<\/ul>\n

                Powder Engineering & Research Handling<\/strong><\/h3>\n

                Our\u00a0micronized 5-MeO-DMT fumarate powder<\/strong>\u00a0(20-60\u03bcm) optimizes\u00a0laboratory manipulation<\/strong>:<\/p>\n

                Solubility Profile:<\/strong><\/p>\n

                  \n
                • Dimethyl sulfoxide (DMSO):<\/strong>\u00a0\u2265100 mg\/mL (preferred stock solvent)<\/li>\n
                • Methanol:<\/strong>\u00a0\u226580 mg\/mL<\/li>\n
                • Water (pH 5-6):<\/strong>\u00a0\u226550 mg\/mL (fumarate salt advantage)<\/li>\n
                • Ethanol:<\/strong>\u00a0\u226560 mg\/mL<\/li>\n
                • Phosphate-buffered saline (PBS):<\/strong>\u00a0\u226530 mg\/mL<\/li>\n
                • Acetonitrile:<\/strong>\u00a0\u226540 mg\/mL<\/li>\n<\/ul>\n

                  Stock Solution Preparation:<\/strong><\/p>\n

                    \n
                  • 10 mM aqueous stock:<\/strong>\u00a0Dissolve 3.48mg in 1mL sterile water (pH adjusted to 5.5-6.5)<\/li>\n
                  • Storage:<\/strong>\u00a0-80\u00b0C in\u00a0aliquoted portions<\/strong>\u00a0to prevent\u00a0freeze-thaw degradation<\/strong><\/li>\n
                  • Working solutions:<\/strong>\u00a0Prepare fresh daily in\u00a0physiological buffers<\/strong><\/li>\n<\/ul>\n

                    Handling Precautions:<\/strong><\/p>\n

                      \n
                    • Anti-static measures:<\/strong>\u00a0Grounded equipment, ionizing blowers (powder generates static)<\/li>\n
                    • Light protection:<\/strong>\u00a0Amber glassware or foil wrapping (photosensitive)<\/li>\n
                    • Oxygen exclusion:<\/strong>\u00a0Argon atmosphere for long-term storage<\/li>\n
                    • Desiccation:<\/strong>\u00a0Maintain <10% RH to prevent\u00a0fumaric acid degradation<\/strong><\/li>\n<\/ul>\n

                      Research Applications & Scientific Significance<\/strong><\/h3>\n

                      5-MeO-DMT fumarate<\/strong>\u00a0serves critical functions in\u00a0multiple research domains<\/strong>:<\/p>\n

                      Neuropharmacology:<\/strong><\/p>\n

                        \n
                      • 5-HT1A receptor affinity<\/strong>\u00a0determination (nanomolar Kd values)<\/li>\n
                      • 5-HT2A functional selectivity<\/strong>\u00a0(G\u03b1q vs. \u03b2-arrestin pathways)<\/li>\n
                      • Default mode network (DMN)<\/strong>\u00a0disruption quantification<\/li>\n
                      • Receptor internalization<\/strong>\u00a0kinetics (trafficking studies)<\/li>\n
                      • Comparison with DMT<\/strong>\u00a0(5-methoxy effect on duration\/potency)<\/li>\n<\/ul>\n

                        Psychopharmacology:<\/strong><\/p>\n

                          \n
                        • Subjective effects modeling<\/strong>\u00a0(mystical experience correlates)<\/li>\n
                        • Tolerance<\/strong>\u00a0and\u00a0cross-tolerance<\/strong>\u00a0investigations<\/li>\n
                        • Set and setting<\/strong>\u00a0experimental controls<\/li>\n
                        • Therapeutic potential<\/strong>\u00a0research (treatment-resistant depression models)<\/li>\n<\/ul>\n

                          Forensic Toxicology:<\/strong><\/p>\n

                            \n
                          • LC-MS\/MS method development<\/strong>\u00a0for\u00a0biological matrices<\/strong><\/li>\n
                          • Retention time libraries<\/strong>\u00a0for\u00a0forensic screening<\/strong><\/li>\n
                          • Metabolite identification<\/strong>\u00a0(6-hydroxy-5-MeO-DMT, bufotenin)<\/li>\n
                          • Toad venom vs. synthetic<\/strong>\u00a0differentiation (isotopic analysis)<\/li>\n<\/ul>\n

                            Receptor Biochemistry:<\/strong><\/p>\n

                              \n
                            • Radioligand binding assays<\/strong>\u00a0([\u00b3H]-5-HT, [\u00b9\u00b2\u2075I]-DOI competition)<\/li>\n
                            • G-protein activation<\/strong>\u00a0(GTP\u03b3S binding)<\/li>\n
                            • Second messenger<\/strong>\u00a0quantification (IP\u2081, calcium flux)<\/li>\n
                            • Receptor crystallography<\/strong>\u00a0(structural biology)<\/li>\n<\/ul>\n

                              Comparative Studies:<\/strong><\/p>\n

                                \n
                              • Structure-activity<\/strong>\u00a0vs.\u00a05-MeO-DiPT<\/strong>,\u00a05-MeO-MiPT<\/strong>,\u00a05-MeO-DALT<\/strong><\/li>\n
                              • Route of administration<\/strong>\u00a0pharmacokinetic comparisons<\/li>\n
                              • Species differences<\/strong>\u00a0(rodent vs. human receptor homology)<\/li>\n<\/ul>\n

                                Global Distribution & Licensed Research Supply<\/strong><\/h3>\n

                                BioSynLab operates\u00a0strict verification protocols<\/strong>\u00a0for\u00a05-MeO-DMT distribution<\/strong>\u00a0given its\u00a0Schedule I status<\/strong>\u00a0in most jurisdictions:<\/p>\n

                                Eligibility Requirements:<\/strong><\/p>\n

                                  \n
                                • DEA Schedule I research registration<\/strong>\u00a0(USA)<\/li>\n
                                • Home Office controlled drug license<\/strong>\u00a0(UK)<\/li>\n
                                • Health Canada exemption<\/strong>\u00a0(Canada)<\/li>\n
                                • Competent authority authorization<\/strong>\u00a0(EU member states)<\/li>\n<\/ul>\n

                                  Packaging & Shipping:<\/strong><\/p>\n

                                    \n
                                  • Cryogenic packaging:<\/strong>\u00a0Dry ice (-78\u00b0C) with\u00a0data loggers<\/strong><\/li>\n
                                  • Discrete outer packaging:<\/strong>\u00a0Unmarked, generic return addresses<\/li>\n
                                  • Documentation:<\/strong>\u00a0Import\/export permits<\/strong>,\u00a0customs declarations<\/strong>\u00a0prepared<\/li>\n
                                  • Insurance:<\/strong>\u00a0Full value coverage with\u00a0licensed courier services<\/strong><\/li>\n
                                  • Chain of custody:<\/strong>\u00a0Tamper-evident seals<\/strong>,\u00a0signature required<\/strong><\/li>\n<\/ul>\n

                                     <\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

                                    Premium 5-MeO-DMT Fumarate Powder: Industrial Grade Research Chemical   Product Details Table   Attribute Specification Brand BioSynLab Research Compounds Product Name 5-MeO-DMT Fumarate IUPAC Name 3-[2-(Dimethylamino)ethyl]-5-methoxyindole fumarate Synonyms 5-Methoxy-DMT, O-methylbufotenin, Toad extract analog CAS Number 96096-55-8 (fumarate salt); 1019-45-0 (freebase) Molecular Formula C\u2081\u2084H\u2082\u2080N\u2082O \u00b7 C\u2084H\u2084O\u2084 Molecular Weight 348.39 g\/mol (salt); 218.29 g\/mol (freebase equivalent) Salt […]<\/p>\n","protected":false},"featured_media":650,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[3723,3380],"product_tag":[17354,17376,17377,17378,17379,17380,17381,17382,17383,17384,17385,17386,17387,17388,17389,22783,22697,22817,22727,17390,22820,22782,17391,22816,22698,22699,22725,22815,22726,22629,22679,22785,22819,22818,17392,22781],"class_list":["post-633","product","type-product","status-publish","has-post-thumbnail","product_cat-5-meo-dmt","product_cat-tryptamines","product_tag-5-meo-dmt-forschung-chemikalie","product_tag-5-meo-dmt-fumarate-solubility","product_tag-5-meo-dmt-fumarate-stability-powder","product_tag-5-meo-dmt-fumarate-suministro-a-granel","product_tag-5-meo-dmt-fumarate-tryptamine-analog","product_tag-5-meo-dmt-fumarate-usa","product_tag-5-meo-dmt-fumarato-laboratorio","product_tag-5-meo-dmt-fumarato-polvo-investigacion","product_tag-5-meo-dmt-polvo-fumarato","product_tag-5-meo-dmt-powder-fumarate","product_tag-5-meo-dmt---","product_tag-5-meo-dmt--","product_tag-5-meo-dmt-","product_tag-belfast","product_tag-birmingham","product_tag-brighton","product_tag-bristol","product_tag-buy-5-meo-dmt-fumarate-bulk","product_tag-cambridge","product_tag-cardiff","product_tag-comprar-5-meo-dmt-fumarato","product_tag-coventry","product_tag-edinburgh","product_tag-glasgow","product_tag-leeds","product_tag-leicester","product_tag-liverpool","product_tag-london","product_tag-manchester","product_tag-nottingham","product_tag-oxford","product_tag-plymouth","product_tag-poudre-5-meo-dmt-fumarate","product_tag-sheffield","first","instock","shipping-taxable","purchasable","product-type-variable"],"yoast_head":"\n5\u2011MeO\u2011DMT Powder (Fumarate) | High\u2011Purity Research<\/title>\n<meta name=\"description\" content=\"uy analytically\u2011pure 5\u2011MeO\u2011DMT Powder (Fumarate) for advanced laboratory applications. 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