{"id":709,"date":"2026-06-07T23:42:31","date_gmt":"2026-06-07T23:42:31","guid":{"rendered":"https:\/\/biosynlab.com\/?post_type=product&p=709"},"modified":"2026-06-21T10:33:52","modified_gmt":"2026-06-21T10:33:52","slug":"body-supplements-nefiracetam-vega-caps-200mg-30-pcs","status":"publish","type":"product","link":"https:\/\/www.biosynlab.com\/?product=body-supplements-nefiracetam-vega-caps-200mg-30-pcs","title":{"rendered":"Body Supplements \u2013 Nefiracetam Vega Caps 200mg (30 pcs)"},"content":{"rendered":"
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BIOSYNLAB Nefiracetam Vega Caps \u2013 200mg (30 Pieces)<\/h1>\n

 <\/p>\n

Product Details Table<\/h2>\n

 <\/p>\n

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\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Specification<\/strong><\/th>\nDetails<\/strong><\/th>\n<\/tr>\n<\/thead>\n
Brand<\/strong><\/td>\nBIOSYNLAB Research Compounds<\/td>\n<\/tr>\n
Product Name<\/strong><\/td>\nNefiracetam (DM-9384) Racetam Nootropic Capsules<\/td>\n<\/tr>\n
IUPAC Name<\/strong><\/td>\nN-(2,6-Dimethylphenyl)-2-(2-oxopyrrolidin-1-yl)acetamide<\/td>\n<\/tr>\n
CAS Number<\/strong><\/td>\n77191-36-7<\/td>\n<\/tr>\n
Synonyms<\/strong><\/td>\nDM-9384, DZL-221, Translon<\/td>\n<\/tr>\n
Molecular Formula<\/strong><\/td>\nC\u2081\u2084H\u2081\u2088N\u2082O\u2082<\/td>\n<\/tr>\n
Molecular Weight<\/strong><\/td>\n246.31 g\/mol<\/td>\n<\/tr>\n
Purity Grade<\/strong><\/td>\n\u226599% (HPLC verified)<\/td>\n<\/tr>\n
Formulation<\/strong><\/td>\n200mg per vegan capsule (30 capsules per container)<\/td>\n<\/tr>\n
Appearance<\/strong><\/td>\nWhite to off-white crystalline powder in plant-based HPMC capsules<\/td>\n<\/tr>\n
Chemical Class<\/strong><\/td>\nRacetam family; Pyrrolidone derivative<\/td>\n<\/tr>\n
Mechanism<\/strong><\/td>\nCholinergic enhancement, GABA modulation, calcium channel modulation<\/td>\n<\/tr>\n
Packaging<\/strong><\/td>\nIndustrial-grade amber PET, nitrogen-flushed, 30-count<\/td>\n<\/tr>\n
Storage<\/strong><\/td>\n2-25\u00b0C room temperature, desiccated, light-protected<\/td>\n<\/tr>\n
Batch Analysis<\/strong><\/td>\nCOA, HPLC chromatogram available<\/td>\n<\/tr>\n
Origin<\/strong><\/td>\nGMP-certified synthesis facility<\/td>\n<\/tr>\n
Shipping<\/strong><\/td>\nTemperature-controlled, discreet, EU-compliant<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n
\n

Advanced Racetam Pharmacology: The Cholinergic-GABAergic Modulator<\/h2>\n

Are you investigating novel mechanisms for cognitive enhancement, neuroprotection after ischemic injury, or antiepileptic compound development?<\/strong>\u00a0BIOSYNLAB<\/a> delivers pharmaceutical-grade Nefiracetam capsules\u2014synthesized to exacting specifications for neuropharmacological research, stroke modeling, and cognitive science laboratories across the USA, Europe, and United Kingdom markets.<\/p>\n

Nefiracetam (DM-9384, Translon)<\/a> represents a second-generation racetam compound developed by Daiichi Seiyaku (Japan), distinguished by its unique 2,6-dimethylphenyl substitution that confers enhanced lipophilicity and distinct receptor pharmacology compared to Piracetam and Aniracetam. This pyrrolidone derivative has emerged as a critical reference compound for investigating multimodal neurotransmitter modulation, synaptic plasticity, and neuroprotection following cerebral hypoxia.<\/p>\n

Our synthesis protocol employs controlled amidation of 2-oxo-1-pyrrolidineacetic acid with 2,6-dimethylaniline, delivering batch-to-batch consistency that meets the demanding standards of receptor pharmacology, electrophysiology, and behavioral neuroscience research.<\/p>\n

\n

Chemical Structure & Mechanism of Action<\/h2>\n

Structural Classification:<\/strong>\u00a0Nefiracetam belongs to the racetam family featuring:<\/p>\n

    \n
  • 2-Oxopyrrolidine core:<\/strong>\u00a0Characteristic pyrrolidone pharmacophore<\/li>\n
  • 2,6-Dimethylphenyl substitution:<\/strong>\u00a0Lipophilic aryl group enhancing membrane permeability<\/li>\n
  • Acetamide linker:<\/strong>\u00a0Hydrogen bond donor\/acceptor for receptor interaction<\/li>\n<\/ul>\n

    Pharmacological Profile:<\/strong><\/p>\n

    Primary Mechanism: Cholinergic Enhancement<\/h3>\n
      \n
    • Acetylcholine release:<\/strong>\u00a0Enhanced presynaptic ACh release in cortex and hippocampus<\/li>\n
    • Choline acetyltransferase (ChAT):<\/strong>\u00a0Upregulation of ACh synthesis enzyme<\/li>\n
    • Nicotinic receptor potentiation:<\/strong>\u00a0Positive allosteric modulation of \u03b14\u03b22 nAChR<\/li>\n
    • Muscarinic signaling:<\/strong>\u00a0Enhanced M1 receptor-mediated phosphoinositide hydrolysis<\/li>\n<\/ul>\n

      Secondary Mechanisms<\/h3>\n
        \n
      • GABA-A receptor modulation:<\/strong>\u00a0Positive allosteric modulation at \u03b2-subunit containing receptors<\/li>\n
      • Calcium channel regulation:<\/strong>\u00a0Inhibition of N-type and T-type calcium channels<\/li>\n
      • AMPA receptor trafficking:<\/strong>\u00a0Enhanced GluR1 subunit membrane insertion<\/li>\n
      • PKC activation:<\/strong>\u00a0Protein kinase C epsilon translocation<\/li>\n<\/ul>\n
        \n

        Industrial Applications & Research Implementations<\/h2>\n

        Neuropharmacological Research<\/h3>\n

        Nefiracetam serves as a critical tool compound for:<\/p>\n

          \n
        • Cognitive enhancement studies<\/strong>\u00a0\u2013 Learning and memory consolidation protocols<\/li>\n
        • Stroke rehabilitation models<\/strong>\u00a0\u2013 Post-ischemic cognitive recovery research<\/li>\n
        • Epilepsy research<\/strong>\u00a0\u2013 Anticonvulsant and neuroprotective mechanism studies<\/li>\n
        • Aging brain research<\/strong>\u00a0\u2013 Age-related cognitive decline intervention models<\/li>\n
        • Depression models<\/strong>\u00a0\u2013 GABA-glutamate balance modulation studies<\/li>\n<\/ul>\n

          Cerebrovascular & Ischemia Research<\/h3>\n
            \n
          • Cerebral ischemia models<\/strong>\u00a0\u2013 MCAO (middle cerebral artery occlusion) protocols<\/li>\n
          • Hypoxic-ischemic encephalopathy<\/strong>\u00a0\u2013 Neonatal brain injury research<\/li>\n
          • Cerebral blood flow<\/strong>\u00a0\u2013 Microcirculation and metabolic coupling studies<\/li>\n<\/ul>\n

            Pharmaceutical Development<\/h3>\n
              \n
            • Racetam SAR studies<\/strong>\u00a0\u2013 Structure-activity relationship optimization<\/li>\n
            • Combination therapy research<\/strong>\u00a0\u2013 Synergistic effects with cholinesterase inhibitors<\/li>\n
            • Formulation development<\/strong>\u00a0\u2013 Bioavailability enhancement protocols<\/li>\n
            • Prodrug synthesis<\/strong>\u00a0\u2013 Ester and amide derivative screening<\/li>\n<\/ul>\n

              Analytical Chemistry<\/h3>\n
                \n
              • HPLC reference standard<\/strong>\u00a0\u2013 Racetam quantification in biological matrices<\/li>\n
              • Mass spectrometry calibration<\/strong>\u00a0\u2013 LC-MS\/MS method development<\/li>\n
              • Forensic toxicology<\/strong>\u00a0\u2013 Novel psychoactive substance screening<\/li>\n<\/ul>\n
                \n

                Synthesis Methodology & Quality Assurance<\/h2>\n

                Manufacturing Protocol:<\/strong><\/p>\n

                  \n
                1. Starting Material:<\/strong>\u00a02-Oxo-1-pyrrolidineacetic acid (pyroglutamic acid derivative)<\/li>\n
                2. Activation:<\/strong>\u00a0Formation of acid chloride or active ester intermediate<\/li>\n
                3. Amidation:<\/strong>\u00a0Reaction with 2,6-dimethylaniline under anhydrous conditions<\/li>\n
                4. Cyclization:<\/strong>\u00a0Intramolecular condensation forming pyrrolidone ring<\/li>\n
                5. Purification:<\/strong>\u00a0Recrystallization from ethanol-water or ethyl acetate<\/li>\n
                6. Drying:<\/strong>\u00a0Vacuum desiccation to <0.5% residual moisture<\/li>\n
                7. Micronization:<\/strong>\u00a0Controlled particle size for optimal dissolution<\/li>\n
                8. Encapsulation:<\/strong>\u00a0200mg precision dosing in vegan HPMC capsules<\/li>\n<\/ol>\n

                  Analytical Verification:<\/strong><\/p>\n

                    \n
                  • HPLC Purity:<\/strong>\u00a0\u226599% (UV detection at 210nm)<\/li>\n
                  • Mass Spectrometry:<\/strong>\u00a0Molecular ion confirmation (m\/z 247.1 [M+H]+)<\/li>\n
                  • NMR Spectroscopy:<\/strong>\u00a0\u00b9H-NMR and \u00b9\u00b3C-NMR structural validation<\/li>\n
                  • Melting Point:<\/strong>\u00a0146-149\u00b0C<\/li>\n
                  • Residual Solvents:<\/strong>\u00a0GC-MS verification (ICH Q3C compliance)<\/li>\n
                  • Heavy Metals:<\/strong>\u00a0ICP-MS screening (Pb, Cd, Hg, As <10 ppm)<\/li>\n
                  • Water Content:<\/strong>\u00a0Karl Fischer titration (<0.5%)<\/li>\n
                  • Uniformity of Dosage:<\/strong>\u00a0USP <905> compliance (200mg \u00b15%)<\/li>\n<\/ul>\n
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                    <\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/form>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

                    BIOSYNLAB Nefiracetam Vega Caps \u2013 200mg (30 Pieces)   Product Details Table   Specification Details Brand BIOSYNLAB Research Compounds Product Name Nefiracetam (DM-9384) Racetam Nootropic Capsules IUPAC Name N-(2,6-Dimethylphenyl)-2-(2-oxopyrrolidin-1-yl)acetamide CAS Number 77191-36-7 Synonyms DM-9384, DZL-221, Translon Molecular Formula C\u2081\u2084H\u2081\u2088N\u2082O\u2082 Molecular Weight 246.31 g\/mol Purity Grade \u226599% (HPLC verified) Formulation 200mg per vegan capsule (30 capsules […]<\/p>\n","protected":false},"featured_media":731,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[5115],"product_tag":[17963,17964,17965,17966,17967,17968,17969,17970,17971,17972,17973,17974,17975,17976,17977,17978,17979,17980,17981,17982,17983,17984,17985,17986,17987,17988,17989,17990,17991,17992,17993,17994,17995,17996,17997],"class_list":["post-709","product","type-product","status-publish","has-post-thumbnail","product_cat-nootropics","product_tag-941-capsules","product_tag-buy-crl-40","product_tag-buy-fladrafinil-capsules-bulk","product_tag-capsulas-de-fladrafinil-50-mg-spanish","product_tag-capsule-fladrafinil-50-mg-italian","product_tag-fladrafinil-caps-forskning-danish-research-use","product_tag-fladrafinil-caps-forskning-norwegian-research","product_tag-fladrafinil-caps-forskning-swedish-research","product_tag-fladrafinil-caps-forskningsbruk-norwegian-research-use","product_tag-fladrafinil-caps-forskningsbruk-swedish-research-use","product_tag-fladrafinil-caps-forskningskemikalie-swedish-research-chemical","product_tag-fladrafinil-caps-onderzoek-dutch-research-use","product_tag-fladrafinil-caps-onderzoek-dutch-research","product_tag-fladrafinil-caps-tutkimus-finnish-research","product_tag-fladrafinil-caps---greek-wholesale","product_tag-fladrafinil-caps--russian-research","product_tag-fladrafinil-caps--bulgarian-research","product_tag-fladrafinil-caps--danish-research","product_tag-fladrafinil-groshandel-german-wholesale","product_tag-fladrafinil-kapseln-50-mg-kaufen-german","product_tag-fladrafinil-kapslar-50-mg-danish","product_tag-fladrafinil-kapslar-50-mg-swedish","product_tag-fladrafinil-research-chemical-supplier","product_tag-fladrafinil-research-grade-europe","product_tag-fladrafinil-vega-caps-50-mg","product_tag-fladrafinil-venta-al-por-mayor-spanish-wholesale","product_tag-fladrafinil-wholesale-europe","product_tag-fladrafinil--50--russian","product_tag-fladrafinil--50-mg-hindi","product_tag-fladrafinil--50-mg-chinese","product_tag-gelules-fladrafinil-50-mg-french","product_tag-neuropharmacology-fladrafinil-studies","product_tag-research-eugeroic-fladrafinil","product_tag-wakefulness-research-chemical","product_tag---50-mg-japanese","first","instock","shipping-taxable","purchasable","product-type-simple"],"yoast_head":"\nBuy Fladrafinil Vega Caps 50\u202fmg (60 capsules) | Research\u2011Grade<\/title>\n<meta name=\"description\" content=\"Premium Nefiracetam 200mg vegan capsules (30 pieces) CAS 77191-36-7. 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