1D-LSD
1D-LSD (1,2-Dimethylcyclobutane-1-carbonyl-LSD) — High-Purity Research Chemical
Chemical & Physical Properties
Product Summary
1D-LSD, formally known as 1-(1,2-dimethylcyclobutane-1-carbonyl)-D-lysergic acid diethylamide and also designated SYN-L-229, is a high-purity lysergamide-class research chemical available at BiosynLab.com for qualified laboratory and in-vitro research applications. 1D-LSD is an N1-acylated derivative of D-lysergic acid diethylamide (LSD) in which the indole nitrogen is substituted with a 1,2-dimethylcyclobutane-1-carbonyl group, a sterically strained acyl moiety that distinguishes it from other N1-acylated lysergamides such as 1P-LSD, 1B-LSD, and 1cP-LSD. This structural feature is of significant scientific interest due to its potential influence on metabolic deacylation kinetics and prodrug activation pathways. Each batch is synthesized under controlled conditions and independently verified through third-party analytical testing to confirm identity, purity, and consistency. Our 1D-LSD is supplied with a complete Certificate of Analysis (COA) documenting purity percentage, analytical methods used, and quality control results, ensuring full traceability from synthesis to shipment.
BiosynLab.com is committed to supplying research-grade compounds that meet the rigorous demands of academic, pharmaceutical, and industrial research institutions. Whether your work involves serotonin receptor binding studies, lysergamide structure-activity relationship (SAR) research, prodrug metabolism investigations, or analytical method development, 1D-LSD from BiosynLab is produced to deliver reproducible, publication-quality results.
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Property
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Details
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Chemical Name (IUPAC)
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(6aR,9R)-4-(1,2-dimethylcyclobutanecarbonyl)-N,N-diethyl-7-methyl-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-9-carboxamide
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Alternative IUPAC Name
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(8β)-1-(1,2-Dimethylcyclobutane-1-carbonyl)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide
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Common Name(s)
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1D-LSD; 1-(1,2-dimethylcyclobutane-1-carbonyl)-LSD; 1-(1,2-dimethylcyclobutane-1-carbonyl)-N,N-diethyllysergamide; SYN-L-229
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CAS Number
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Not yet assigned / pending
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PubChem CID
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170703347
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Molecular Formula
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C27H35N3O2
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Molecular Weight
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433.6 g/mol
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Appearance
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White to off-white crystalline solid
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Purity
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≥ 98% (determined by HPLC)
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Solubility
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Soluble in DMSO, ethanol, and methanol; limited solubility in water
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LogP (XLogP3)
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4.6
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Topological Polar Surface Area
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45.6 Ų
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Hydrogen Bond Donors
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0
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Hydrogen Bond Acceptors
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3
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SMILES
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CCN(CC)C(=O)C1CN(C2CC3=CN(C4=CC=CC(=C34)C2=C1)C(=O)C5(CCC5C)C)C
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InChIKey
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RNVFVHAKGPSAIU-ZRCBXKLVSA-N
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Storage Conditions
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Store at −20°C, protected from light and moisture, under inert atmosphere
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Shelf Life
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24 months from manufacture date when stored as directed
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Synthesis & Quality Control
Every batch of 1D-LSD produced at BiosynLab is manufactured in compliance with stringent quality management protocols. The 1,2-dimethylcyclobutane-1-carbonyl acyl group presents unique synthetic challenges compared to simpler N1-acyl lysergamides, requiring specialized acylation methodologies and rigorous purification. Our synthesis pipeline follows documented standard operating procedures (SOPs), and each production run undergoes multi-stage quality verification before release.
Analytical testing typically includes:
Showing all 3 resultsSorted by popularity
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1D-LSD Blotters – 150mcg
Price range: $59.50 through $695.00 Select options This product has multiple variants. The options may be chosen on the product page -

1D-LSD Pellets – 225mcg
Price range: $87.50 through $930.00 Select options This product has multiple variants. The options may be chosen on the product page -

1D-LSD Micro Pellets – 10mcg
Price range: $12.50 through $500.00 Select options This product has multiple variants. The options may be chosen on the product page
