Description
BIOSYNLAB Ginkgo Biloba Capsules – 60mg Neurovascular Research Standard
Product Details Table
| Specification | Details |
|---|---|
| Brand | BIOSYNLAB Research Compounds |
| Product Name | Ginkgo Biloba Standardized Extract 60mg |
| Botanical Source | Ginkgo biloba L. – Premium leaf extract |
| CAS Number | 90045-36-6 |
| Standardization | EGb761 profile: 24% flavone glycosides, 6% terpene lactones |
| Active Compounds | Ginkgolide A/B/C, Bilobalide, Quercetin, Kaempferol, Isorhamnetin |
| Formulation | 60mg per vegetarian capsule |
| Purity Grade | ≥99% HPLC verified |
| Mechanism | PAF antagonist, antioxidant, NO modulator |
| Appearance | Brown powder in clear HPMC capsules |
| Extraction | Acetone-water (EGb761 protocol) |
| Packaging | Amber PET, nitrogen-flushed, tamper-evident |
| Storage | 15-25°C, desiccated, light-protected |
| COA | Available per batch |
| Origin | GMP-certified facility |
| Shipping | Temperature-controlled, EU-compliant |
The Living Fossil of Neuropharmacology
Investigating platelet-activating factor antagonism, cerebral microcirculation, or antioxidant neuroprotection mechanisms? BIOSYNLAB delivers research-grade Ginkgo Biloba standardized to the EGb761 pharmacological profile—engineered for neurovascular laboratories, stroke research facilities, and cognitive pharmacology studies across USA, Europe, and UK.
Ginkgo biloba, the sole surviving species of the division Ginkgophyta, represents 270 million years of evolutionary biochemistry. Our standardized extract captures this ancient pharmacopeia in precise 60mg doses, delivering consistent concentrations of ginkgolides and bilobalide—the terpene lactones responsible for PAF receptor antagonism and neuroprotective activity.
Each batch is verified for 24% flavone glycosides and 6% terpene lactones via HPLC, ensuring reproducible results in receptor binding assays, platelet aggregation studies, and oxidative stress models.
Mechanism of Action: PAF & Beyond
Platelet-Activating Factor (PAF) Antagonism
- Ginkgolides A/B/C competitively inhibit PAF receptor (PAFR)
- Reduces platelet aggregation and thrombus formation
- Improves cerebral blood flow and microcirculation
Nitric Oxide Modulation
- Enhances endothelial NO synthase (eNOS) activity
- Promotes vasodilation and vascular compliance
- Supports neurovascular coupling
Antioxidant Cascade
- Flavonoids scavenge free radicals (ROS, RNS)
- Upregulates SOD, catalase, GPx expression
- Chelates heavy metals (Fe²⁺, Cu²⁺)
Mitochondrial Protection
- Bilobalide enhances mitochondrial function
- Reduces cytochrome c release
- Anti-apoptotic signaling via Bcl-2 pathway
Research Applications
Cerebrovascular Studies
- Post-stroke neuroprotection models
- Cerebral ischemia-reperfusion injury
- Microcirculation and capillary perfusion
- Vascular dementia mechanisms
Neurodegenerative Research
- Alzheimer’s disease models (amyloid-β, tau pathology)
- Parkinson’s disease (dopaminergic protection)
- Oxidative stress in aging brain
- Mitochondrial dysfunction studies
Cognitive Pharmacology
- Memory consolidation mechanisms
- Attention and executive function
- Neuroplasticity and synaptic plasticity
- Cognitive aging interventions
Hemorheological Assays
- Platelet aggregation inhibition (PAF-induced)
- Blood viscosity modulation
- Erythrocyte deformability
- Coagulation cascade studies
Production & Quality
Extraction Protocol:
- Certified G. biloba leaves, sustainable harvest
- Acetone-water extraction (60:40)
- Multi-stage purification (<5 ppm ginkgolic acids)
- Standardization to 24% flavone glycosides, 6% terpenes
- Spray-drying with maltodextrin
- Precision encapsulation (60mg ±5%)
Quality Verification:
- HPLC: Ginkgolides A/B/C, bilobalide quantification
- UV: Total flavone glycosides (24% ±2%)
- ICP-MS: Heavy metals compliance
- Microbial: USP <61> standards
- Identity: TLC fingerprinting
Responsible Use Disclaimer
⚠️ Research Use Only
Sold strictly for laboratory analysis, research, and industrial applications. Not for human consumption without regulatory approval. Handle with PPE. Consult MSDS. Comply with local regulations.
Regulatory: Classified as traditional herbal medicinal product (EU THR) and dietary supplement (US FDA). This research-grade product not intended for consumer use.
Storage: 36-month stability at 15-25°C. Protect from moisture and light.
Why Choose BIOSYNLAB
- EGb761-equivalent standardization
- Batch-to-batch HPLC consistency
- Full COA and documentation
- REACH-registered, EU-compliant
- PhD-level technical support
- Secure international shipping
Contact BIOSYNLAB for bulk pricing, custom formulations, or technical consultation on PAF antagonism and neurovascular research applications.
