Description
Crack Cocaine (Cocaine Base, Freebase
PRODUCT DETAILS TABLE
| Specification | Details |
|---|---|
| Brand | Biosynlab |
| Product Name | Crack Cocaine (Cocaine Base, Freebase) |
| IUPAC Name | methyl (1R,2R,3S,5S)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate (base form) |
| CAS Number | 50-36-2 (cocaine); base form unnumbered |
| Molecular Formula | C₁₇H₂₁NO₄ |
| Molecular Weight | 303.35 g/mol |
| Chemical Class | Tropane alkaloid / Stimulant |
| Purity | ≥99.0% (HPLC Verified) |
| Appearance | White to off-white crystalline rocks or powder (base); yellowish (impure) |
| Melting Point | 98-102°C (base form, decomposes) |
| Solubility | Soluble in ethanol, chloroform, ether; insoluble in water |
| Storage | -20°C, desiccated, away from light, inert atmosphere |
| Packaging | Amber glass vial with PTFE seal, inert atmosphere |
| Quantities | 100mg, 250mg, 500mg, 1g, bulk (licensed institutions only) |
| Analysis | COA, NMR, MS, FTIR included |
| Shipping | Express courier, tracked, discreet, signature required |
| Regions | USA (DEA licensed), UK (Home Office), Germany, Netherlands, EU |
Crack Cocaine (Cocaine Base, Freebase represents the alkaloidal freebase form of cocaine, serving as a critical reference standard in forensic toxicology, pharmaceutical research, and criminalistics applications. As the unprotonated base form of cocaine hydrochloride, crack cocaine exhibits distinct physicochemical properties including lower melting point, enhanced lipid solubility, and volatility characteristics that differentiate it from the salt form. Biosynlab delivers pharmaceutical-grade cocaine base with certified ≥99.0% purity, supporting cutting-edge research across USA (DEA-licensed institutions), United Kingdom (Home Office licensed), European Union, and international forensic and analytical markets.
The deprotonation of cocaine hydrochloride to the freebase form fundamentally alters solubility, melting behavior, and pharmacokinetic properties. This chemical modification creates distinct analytical signatures that make cocaine base invaluable for comparative studies with cocaine HCl, forensic sample profiling, and understanding the chemistry of illicit drug manufacture. Forensic laboratories in London, Berlin, Amsterdam, New York, and Los Angeles rely on Biosynlab cocaine base for quantitative analysis in seizure evidence, smoking paraphernalia residue analysis, and differentiation of cocaine salt vs. base forms in criminalistics investigations.
Chemical Properties & Structural Characterization
Cocaine Base belongs to the tropane alkaloid chemical class, specifically the ecgonine derivative subclass characterized by a bicyclic [3.2.1] azabicyclooctane ring system with characteristic ester substitutions.
Key Structural Features:
- Core Scaffold: Tropane (8-azabicyclo[3.2.1]octane) ring system
- Substituents: 3β-benzoyloxy, 2β-methoxycarbonyl, N-methyl
- Stereochemistry: (1R,2R,3S,5S) absolute configuration
- Functional Groups: Tertiary amine (basic nitrogen), benzoate ester, methyl ester
- Physical Form: Crystalline base (rocks, “crack”) or powder
- Volatility: Thermally unstable, sublimes/decomposes on heating
Analytical Characteristics:
- UV Absorption: 230 nm (benzoate chromophore), 275 nm shoulder
- Retention Time (HPLC): 9.2-10.1 minutes (base form, C18 column)
- Mass Spec m/z: 304.2 [M+H]+ (base peak), 182.1 [ecgonine methyl ester]+, 105.1 [benzoyl]+, 82.1 [tropane]+
- NMR Signatures: Tropane bridge protons (3.5-4.0 ppm), N-methyl singlet (2.3-2.5 ppm), aromatic protons (7.4-8.0 ppm), methoxycarbonyl singlet (3.6-3.8 ppm)
